Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.87 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL27831880 | 0.97 | ALDH1A1 (0.81) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL1332089 | 0.93 | — | — | |
| SCHEMBL1958756 | 0.93 | ALDH1A1 (1.00) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL3673 | 0.93 | — | — | |
| Bicarbonate SCHEMBL23051690 | 0.91 | ALDH1A1 (0.72) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Ethylene Glycol SCHEMBL1274144 | 0.90 | ALDH1A1 (0.81) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| Charcoal, Activated SCHEMBL1901032 | 0.90 | — | — | |
| SCHEMBL544742 | 0.90 | — | — | |
| Water SCHEMBL22362219 | 0.90 | — | — | |
| Bromide SCHEMBL10459370 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057579-A | Method for preparing asymmetric carbonate by rectifying catalytic reaction of symmetric carbonate | 河北工业大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-113061087-A | Method and device for producing methyl ethyl carbonate | 河南红东方化工股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10944119-B2 | Methods and devices for storage and release of hydrogen | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2021-03-09 | — | — | US | disclosed |
| CN-106748782-B | A kind of method of magnesium aluminium lanthanum composite oxide catalytic Catalysts of Preparing Methyl Ethyl Carbonate | 邵阳学院 | 2019-11-08 | — | — | CN | disclosed |
| CN-106748781-B | A kind of method that calcium and magnesium aluminium composite oxide catalyzes and synthesizes methyl ethyl carbonate | 邵阳学院 | 2019-10-11 | — | — | CN | disclosed |
| CN-106588659-B | A method of roasting state hydrocalumite catalyzes and synthesizes methyl ethyl carbonate | 邵阳学院 | 2019-05-14 | — | — | CN | disclosed |
| CN-109180490-A | The lithium electricity homogeneous production technology of high-purity diethyl carbonate | 沈阳化工大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-106748781-A | A kind of method that calcium and magnesium aluminium composite oxide catalyzes and synthesizes methyl ethyl carbonate | 邵阳学院 | 2017-05-31 | — | — | CN | disclosed |
| CN-106748782-A | A kind of method of magnesium aluminium lanthanum composite oxide catalytic Catalysts of Preparing Methyl Ethyl Carbonate | 邵阳学院 | 2017-05-31 | — | — | CN | disclosed |
| CN-106588659-A | Method for synthesizing methyl ethyl carbonate under catalysis of roasted-state hydrocalumite | 邵阳学院 | 2017-04-26 | — | — | CN | disclosed |
| CN-103214373-B | Ethyl methyl carbonate synthesis method | UNIV SHANDONG | 2014-08-06 | — | — | CN | disclosed |
| CN-103214373-A | Ethyl methyl carbonate synthesis method | UNIV SHANDONG | 2013-07-24 | — | — | CN | disclosed |
| EP-1789070-B1 | TAJ IN NEURONAL FUNCTION | BIOGEN IDEC INC (US) | 2012-10-24 | — | — | EP | disclosed |
| CN-102212010-A | Method for synthesizing methyl ethyl carbonate | UNIV CHANGZHOU | 2011-10-12 | — | — | CN | disclosed |
| US-7417156-B2 | Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers | JOHNS HOPKINS UNIVERSITY (US) | 2008-08-26 | — | — | US | disclosed |
| US-20060142377-A1 | Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high selectively, stability and efficacy and methods of making the same | JOHNS HOPKINS UNIVERSITY-LICENSE & TECHNOLOGY DEVE (US) | 2006-06-29 | — | — | US | disclosed |
| WO-2004028476-A2 | ARTEMISININ-DERIVED TRIOXANE DIMERS | JOHNS HOPKINS UNIVERSITY (US) | 2004-04-08 | — | — | WO | disclosed |
| US-4749755-A | BLENDED,COEXTRUDED WITH POLYCARBONATES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142377-A1 | Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high selectively, stability and efficacy and methods of making the same | HCCS, ACIN1, ADH1A | ALDH1A1 175/4885SOAT1 902/4885LMNA 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.