SCHEMBL4868007

SCHEMBL4868007

CCCCc1ccccc1C(=O)C(OC)C(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
ELANE P08246 1/20 0.38
CTRC Q99895 1/20 0.38
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYSLTR2 Q9NS75 6/20 0.38
CYSLTR1 Q9Y271 6/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
PGR P06401 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30557597 0.90 ELANE (0.40) PPARAKMT2AKDM4EMEN1RECQL
SCHEMBL6269193 0.87 CYP3A4 (0.43) PPARAKMT2AKDM4EMEN1TSHR
SCHEMBL31092018 0.84 PPARA (0.38) PPARAKMT2AKDM4EMEN1RECQL
SCHEMBL633584 0.82 TRPV1 (0.54) KMT2AMEN1ALDH1A1
SCHEMBL545445 0.78 CYP4F2 (0.47) PPARACES2CES1
SCHEMBL11397191 0.78 TSHR (0.43) KMT2AKDM4EMEN1RECQLTSHR
SCHEMBL146504 0.77 TSHR (0.52) KMT2AMEN1CES2CES1TSHR
SCHEMBL7164776 0.76 AKR1C3 (0.48) CES2CES1L3MBTL1ALDH1A1
SCHEMBL10772180 0.76 AKR1C3 (0.48) KMT2AKDM4ETSHRTDP1L3MBTL1
SCHEMBL32682105 0.76 PTPN11 (0.45) KMT2AMEN1TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2717970-A2 POLYETHYLENE GLYCOL-FREE COSMETIC OR DERMATOLOGICAL PREPARATIONS Beiersdorf AG (DE) 2014-04-16 EP disclosed
WO-2012167905-A2 POLYETHYLENE GLYCOL-FREE COSMETIC OR DERMATOLOGICAL PREPARATIONS BEIERSDORF AG (DE) 2012-12-13 WO disclosed
WO-2012167906-A2 COSMETIC OR DERMATOLOGICAL PREPARATIONS WITH IMPROVED RHEOLOGICAL PROPERTIES BEIERSDORF AG (DE) 2012-12-13 WO disclosed
US-20080280997-A1 Novel Pharmaceutical or Cosmetic Carriers Containing Cyclic Acetals GATTEFOSSE SAS (FR) 2008-11-13 US disclosed
EP-1737495-A1 NOVEL PHARMACEUTICAL OR COSMETIC CARRIERS CONTAINING CYLCIC ACETALS GATTEFOSSE SAS (FR) 2007-01-03 EP disclosed
WO-2005105149-A1 NOVEL PHARMACEUTICAL OR COSMETIC CARRIERS CONTAINING CYLCIC ACETALS GATTEFOSSE SAS (FR) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080280997-A1 Novel Pharmaceutical or Cosmetic Carriers Containing Cyclic Acetals ACAT2, ACACB, ACAT1 PPARA 277/4885KMT2A 1626/4885KDM4E 2711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.