SCHEMBL486843

SCHEMBL486843

Nc1ccc(Oc2ccc(Oc3ccc(Oc4ccccc4Oc4ccc(Oc5ccc(Oc6ccc(N)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.73
ALDH1A1 P00352 7/20 0.70
TDP1 Q9NUW8 2/20 0.70
CYP3A4 P08684 1/20 0.70
TSHR P16473 1/20 0.70
NCOA1 Q15788 1/20 0.64
NCOA3 Q9Y6Q9 1/20 0.64
MAPT P10636 4/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
MITF O75030 1/20 0.60
GAA P10253 1/20 0.60
GFER P55789 1/20 0.60
NLRP1 Q9C000 1/20 0.60
NOD2 Q9HC29 1/20 0.60
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
NLRP3 Q96P20 1/20 0.57
MAPK1 P28482 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487016 1.00 MAOA (0.73) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL6290540 1.00 MAOA (0.73) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL6290510 0.98 MAOA (0.70) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL6293265 0.98 MAOA (0.70) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL6289838 0.98 MAOA (0.70) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL1270920 0.97 MAOA (0.68) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL459355 0.97 MAOA (0.68) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL29476109 0.97 MAOA (0.68) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL6290292 0.95 MAOA (0.65) MAOAALDH1A1TDP1CYP3A4TSHR
SCHEMBL2252749 0.95 MAOA (0.65) MAOAALDH1A1TDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412743-B1 THERMOSETTING RESIN COMPOSITION, AND PREPREG, INSULATING FILM WITH SUPPORT, LAMINATE PLATE, AND PRINTED WIRING BOARD, EACH OBTAINED USING SAME HITACHI CHEMICAL CO LTD (JP) 2020-08-19 EP disclosed
US-10119047-B2 Thermosetting resin composition, and prepreg, insulating film with support, laminate plate, and printed wiring board, each obtained using same HITACHI CHEMICAL COMPANY, LTD. (JP) 2018-11-06 US disclosed
US-20150203715-A1 Thermosetting Resin Composition, and Prepreg, Insulating Film With Support, Laminate Plate, and Printed Wiring Board, Each Obtained Using Same RESONAC CORPORATION (JP) 2015-07-23 US disclosed
US-20130330563-A1 MODIFIED SILICONE COMPOUND, AND THERMOSETTING RESIN COMPOSITION, PREPREG, LAMINATE PLATE AND PRINTED WIRING BOARD USING SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-12-12 US disclosed
EP-2666804-A1 MODIFIED SILICONE COMPOUND, AND THERMOSETTING RESIN COMPOSITION, PREPREG, LAMINATE PLATE AND PRINTED WIRING BOARD USING SAME Hitachi Chemical Co., Ltd. (JP) 2013-11-27 EP disclosed
US-20120077401-A1 RESIN COMPOSITION FOR PRODUCTION OF CLAD LAYER, RESIN FILM FOR PRODUCTION OF CLAD LAYER UTILIZING THE RESIN COMPOSITION, AND OPTICAL WAVEGUIDE AND OPTICAL MODULE EACH UTILIZING THE RESIN COMPOSITION OR THE RESIN FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-03-29 US disclosed
EP-2412743-A1 THERMOSETTING RESIN COMPOSITION, AND PREPREG, INSULATING FILM WITH SUPPORT, LAMINATE PLATE, AND PRINTED WIRING BOARD, EACH OBTAINED USING SAME Hitachi Chemical Company, Ltd. (JP) 2012-02-01 EP disclosed
US-6933411-B2 Aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2005-08-23 US disclosed
US-6737503-B2 LOW TEMPERATURE ADHESIVE BONDING MITSUI CHEMICALS, INC. (JP) 2004-05-18 US disclosed
US-20040082754-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2004-04-29 US disclosed
US-20030092870-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092870-A1 Novel aromatic diamine and polyimide thereof DDT, AOC1, H1-4 MAOA 372/4885ALDH1A1 902/4885TDP1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.