SCHEMBL459355

SCHEMBL459355

Nc1ccc(Oc2ccccc2Oc2ccc(N)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.68
NCOA1 Q15788 1/20 0.67
NCOA3 Q9Y6Q9 1/20 0.67
ALDH1A1 P00352 7/20 0.65
TDP1 Q9NUW8 3/20 0.65
CYP3A4 P08684 1/20 0.65
TSHR P16473 1/20 0.65
MAPK1 P28482 3/20 0.58
HTT P42858 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
GAA P10253 2/20 0.56
MITF O75030 1/20 0.56
GFER P55789 1/20 0.56
NLRP1 Q9C000 1/20 0.56
NOD2 Q9HC29 1/20 0.56
NPC1 O15118 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476109 1.00 MAOA (0.68) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL1270920 1.00 MAOA (0.68) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL486843 0.97 MAOA (0.73) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL6290292 0.97 MAOA (0.65) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL487016 0.97 MAOA (0.73) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL2252749 0.97 MAOA (0.65) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL6290540 0.97 MAOA (0.73) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL1270898 0.97 MAOA (0.65) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL4263210 0.95 MAOA (0.77) MAOANCOA1NCOA3ALDH1A1TDP1
SCHEMBL6290510 0.95 MAOA (0.70) MAOANCOA1NCOA3ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 566 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060161-A Water-soluble PI, PI composite cellulose, semi-solid electrolyte membrane and preparation method 桂林奇宏科技有限公司 2026-05-19 CN claimed
US-12589581-B2 Thin film capacitor Meta Synthesis Materials Co., Ltd. (TW) 2026-03-31 US claimed
CN-115260571-B High-strength polyimide aerogel fiber and preparation method thereof 优澎(嘉兴)新材料科技有限公司 2025-04-29 CN claimed
CN-119480448-A Thin film capacitor 明盈应材股份有限公司 2025-02-18 CN claimed
WO-2025030690-A1 SOLUBLE POLYIMIDE CASTING SOLUTION, THERMOPLASTIC POLYIMIDE FILM SINTERING LINE AND PREPARATION METHOD THEREFOR AND USE THEREOF 合肥汉之和新材料科技有限公司 2025-02-13 WO claimed
US-20250054696-A1 THIN FILM CAPACITOR Meta Synthesis Materials Co., Ltd. (TW) 2025-02-13 US claimed
WO-2024216910-A1 HIGH-CHEMICAL-RESISTANCE POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 明士(北京)新材料开发有限公司 2024-10-24 WO claimed
CN-116905120-A Polyimide composite aerogel fiber and preparation method thereof 优澎(嘉兴)新材料科技有限公司 2023-10-20 CN claimed
CN-116813488-A Preparation method of bis (4-aminophenoxy) benzene compound 天津众泰材料科技有限公司 2023-09-29 CN claimed
US-11746083-B2 Compound, resin composition and laminated substrate thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-09-05 US claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 US claimed
EP-1424352-A1 Low temperature polymide adhesive compositions and methods relating thereto E.I.Du pont de nemours and company (US) 2004-06-02 EP claimed
US-20040099374-A1 Low temperature polyimide adhesive compositions and methods relating thereto DUPONT ELECTRONICS, INC. 2004-05-27 US claimed
US-5411765-A Coating a polyamic acid film, polyimide gel film and curing E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-05-02 US claimed
US-5298331-A Metal clad laminates for printed circuits and tape automated bonding E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-29 US claimed
US-4520075-A ADHESION, WATERPROOF COATING NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-05-28 US claimed
US-4499252-A Process for producing polyimide precursor NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1985-02-12 US claimed
US-4170684-A ENAMEL LACQUERS FOR WIRES DR. BECK & CO. A.G. (DE) 1979-10-09 US claimed
US-4145334-A POLYESTER IMIDE RESINS DR. BECK & CO., A.G. (DE) 1979-03-20 US claimed
US-3975330-A Imide-modified polyester resin and wire enamel containing the imide-modified polyester resin NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746083-B2 Compound, resin composition and laminated substrate thereof ALOX12, ALOX15, ALOX5 MAOA 1099/4885NCOA1 820/4885NCOA3 2094/4885
US-12589581-B2 Thin film capacitor L1CAM, CHRM1, CHRM2 MAOA 2775/4885NCOA1 1549/4885NCOA3 2745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.