Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL29353383 | 1.00 | ALDH1A1 (0.61) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL1896603 | 0.96 | ALDH1A1 (0.61) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL27931439 | 0.96 | ALDH1A1 (0.61) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL2027808 | 0.93 | ALDH1A1 (0.54) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL8720508 | 0.93 | ALDH1A1 (0.70) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL3960987 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL1929976 | 0.91 | ALDH1A1 (0.61) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL234375 | 0.91 | ALDH1A1 (0.67) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL2326170 | 0.91 | ALDH1A1 (0.67) | ALDH1A1ALOX15CA2CA4CA12 | |
| Phthalic Acid SCHEMBL8474758 | 0.91 | ALDH1A1 (0.67) | ALDH1A1ALOX15CA2CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2224 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115509-A1 | A PROBIOTIC GRANULE HAVING A UNIFIED STABILIZING COATING AND A METHOD FOR THE PRODUCTION THEREOF | AMD PHARMA LTD (IL) | 2024-04-11 | — | — | US | claimed |
| EP-4291210-A1 | A PROBIOTIC GRANULE HAVING A UNIFIED STABILIZING COATING AND A METHOD FOR THE PRODUCTION THEREOF | AMD Pharma Ltd. (IL) | 2023-12-20 | — | — | EP | claimed |
| US-11648198-B2 | Expandable gastroretentive dosage form | CLEXIO BIOSCIENCES LTD. (IL) | 2023-05-16 | — | — | US | claimed |
| US-11039637-B2 | Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof | DEGAMA BERRIER LTD. (KY) | 2021-06-22 | — | — | US | claimed |
| EP-3391876-B1 | LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL | SDG INC (US) | 2021-03-10 | — | — | EP | claimed |
| US-20200405635-A1 | EXPANDABLE GASTRORETENTIVE DOSAGE FORM | CLEXIO BIOSCIENCES LTD. (IL) | 2020-12-31 | — | — | US | claimed |
| EP-3391876-A1 | LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL | SDG, Inc. (US) | 2018-10-24 | — | — | EP | claimed |
| EP-3328364-A1 | NOVEL DUAL DELAYED RELEASE ORAL COMPOSITION OF DEXLANSOPRAZOLE | Zim Laboratories Limited (IN) | 2018-06-06 | — | — | EP | claimed |
| EP-1883394-B1 | LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL | SDG INC (US) | 2018-03-28 | — | — | EP | claimed |
| EP-2521547-B1 | METHODS AND COMPOSITIONS FOR APPLYING MOXIFLOXACIN TO THE EAR | UNIV MINNESOTA (US) | 2017-08-16 | — | — | EP | claimed |
| EP-0227093-B1 | CELLULOSIC BINDER FOR DYE-DONOR ELEMENT USED IN THERMAL DYE TRANSFER | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-11-07 | — | — | EP | claimed |
| US-4916044-A | STORAGE STABLE, SHARP IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-10 | — | — | US | claimed |
| US-4833063-A | Color diffusion transfer element comprising two neutralizing layers and two timing layers | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-23 | — | — | US | claimed |
| EP-0311840-A2 | Polymeric binder for amino-modified silicone slipping layer for dye-donor element used in thermal dye transfer | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-19 | — | — | EP | claimed |
| US-4753920-A | PRINTS FROM VIDEO TAPES | EASTMAN KODAK COMPANY (US) | 1988-06-28 | — | — | US | claimed |
| US-4713079-A | SPHERES; BUFFERS, BINDERS, CONTROLLED PH, INORGANIC FILLERS; LOW DAMAGE TO FABRICS, ELIMINATES PINHOLING | LEVER BROTHERS COMPANY (US) | 1987-12-15 | — | — | US | claimed |
| US-4700207-A | CELLULOSE TRIACETATE OR CELLULOSE MIXED ESTER | EASTMAN KODAK COMPANY (US) | 1987-10-13 | — | — | US | claimed |
| EP-0227093-A2 | Cellulosic binder for dye-donor element used in thermal dye transfer | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-07-01 | — | — | EP | claimed |
| US-4401746-A | Stripping layer consisting of a mixture of cellulose acetate hydrogen phthalate and straight chain saturated polyester of adipic acid | POLAROID CORPORATION (US) | 1983-08-30 | — | — | US | claimed |
| US-4188215-A | Photosensitive printing plate, method of preparing same, and method of processing same | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | claimed |