SCHEMBL486900

SCHEMBL486900

CC(=O)OCC(COP(=O)(O)OCCNC(=O)CCCCC1SC[C@@H]2NC(=O)N[C@H]12)OC(C)=O.CCN(CC)CC

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.53
▸ PRSS1 P07477 1/20 0.53
▸ PRSS2 P07478 1/20 0.53
▸ PRSS3 P35030 1/20 0.53
▸ TPSAB1 Q15661 1/20 0.53
▸ PLCD1 P51178 1/20 0.52
▸ CNR2 P34972 2/20 0.48
▸ CNR1 P21554 3/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ FOLH1 Q04609 3/20 0.44
▸ PKM P14618 2/20 0.43
▸ HPSE Q9Y251 1/20 0.43
▸ CA12 O43570 1/20 0.42
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CA9 Q16790 1/20 0.42
▸ CAPN1 P07384 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028171 0.98 PLCD1 (0.55) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL486814 0.96 PLCD1 (0.56) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL3614161 0.94 PLCD1 (0.59) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL487698 0.90 PLCD1 (0.44) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL1270689 0.90 PLCD1 (0.44) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL20500226 0.85 PLCD1 (0.48) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL2028172 0.85 F2 (0.51) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL10140249 0.85 CNR2 (0.66) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL30165784 0.85 CNR2 (0.66) F2PRSS1PRSS2PRSS3TPSAB1
SCHEMBL28352827 0.84 TDP1 (0.50) F2PRSS1PRSS2PRSS3TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 — — US claimed
EP-3391876-B1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2021-03-10 — — EP claimed
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG INC (US) 2020-12-31 — — US claimed
US-10568835-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2020-02-25 — — US claimed
EP-3391876-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, Inc. (US) 2018-10-24 — — EP claimed
US-20150125518-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. 2015-05-07 — — US claimed
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. (US) 2013-07-18 — — US claimed
EP-2410991-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (an Ohio Corporation ) (US) 2012-02-01 — — EP claimed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 — — US claimed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 — — US claimed
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 — — EP disclosed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 — — US disclosed
EP-3391876-B1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2021-03-10 — — EP disclosed
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG INC (US) 2020-12-31 — — US disclosed
US-10751418-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2020-08-25 — — US disclosed
US-20100247625-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-09-30 — — US disclosed
WO-2010080976-A1 INSULIN THERAPIES FOR THE TREATMENT OF DIABETES, DIABETES RELATED AILMENTS, AND/OR DISEASES OR CONDITIONS OTHER THAN DIABETES OR DIABETES RELATED AILMENTS SDG, INC. (AN OHIO CORPORATION) (US) 2010-07-15 — — WO disclosed
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. 2010-05-27 — — US disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 — — US disclosed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10568835-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 F2 2636/4885PRSS1 981/4885PRSS2 858/4885
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC F2 2252/4885PRSS1 1301/4885PRSS2 609/4885
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL HAVCR2, IFNAR1, IFNG F2 2498/4885PRSS1 2887/4885PRSS2 3300/4885
US-20150125518-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 F2 2636/4885PRSS1 981/4885PRSS2 858/4885
US-20130183270-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC F2 2252/4885PRSS1 1301/4885PRSS2 609/4885
US-11517529-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 F2 2636/4885PRSS1 981/4885PRSS2 858/4885
US-20200405638-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 F2 2636/4885PRSS1 981/4885PRSS2 858/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 F2 2357/4885PRSS1 845/4885PRSS2 302/4885
US-10751418-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 F2 2636/4885PRSS1 981/4885PRSS2 858/4885
US-20100247625-A1 Orally Bioavailable Lipid-Based Constructs FABP2, LIPC, FABP6 F2 1894/4885PRSS1 4150/4885PRSS2 3555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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