SCHEMBL4869337

SCHEMBL4869337

CC(C)CCCC(C)CCCC(C)CCC(O)(P=O)C(CCC(N)=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.42
ALOX15 P16050 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
PTPN1 P18031 3/20 0.34
PTPN2 P17706 1/20 0.34
CDC25B P30305 1/20 0.34
LMNA P02545 1/20 0.33
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4870225 1.00 BLM (0.42) BLMALOX15KMT2AMEN1CYP3A4
SCHEMBL4872956 0.84 ALOX15 (0.31) BLMALOX15KMT2APMP22
SCHEMBL4869123 0.80 TSHR (0.36) KMT2AMEN1CYP3A4
SCHEMBL4870216 0.80 BLM (0.42) BLMALOX15KMT2AMEN1CYP3A4
SCHEMBL4869330 0.80 BLM (0.42) BLMALOX15KMT2AMEN1CYP3A4
SCHEMBL4875397 0.78 ALOX15 (0.37) BLMALOX15KMT2APMP22
SCHEMBL4869941 0.77 HSPD1 (0.40) BLMKMT2AMEN1CYP3A4
SCHEMBL4874676 0.76 ALOX15 (0.35) BLMALOX15KMT2APMP22
SCHEMBL20994108 0.73 BLM (0.55) BLMALOX15KMT2AMEN1CYP3A4
SCHEMBL21417696 0.72 BLM (0.57) BLMALOX15KMT2AMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402576-B2 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2008-07-22 US disclosed
EP-1599487-B1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2007-07-11 EP disclosed
US-20060052616-A1 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2006-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052616-A1 Phosphinic acid analogs of glutamate GLUL, GRIA1, GRM1 BLM 4339/4885ALOX15 852/4885KMT2A 1441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.