SCHEMBL486944

SCHEMBL486944

CCCCCCCCC(C(C)=O)C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.47
ZDHHC7 Q9NXF8 1/20 0.46
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GPR84 Q9NQS5 6/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
CPB2 Q96IY4 1/20 0.41
ATM Q13315 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6309982 1.00 FAAH (0.47) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL1393537 1.00 FAAH (0.47) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL11358682 1.00 FAAH (0.47) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL1393272 1.00 FAAH (0.47) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL4904972 1.00 FAAH (0.47) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL873537 1.00 FAAH (0.47) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL28280400 0.98 FAAH (0.46) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL4135628 0.98 FAAH (0.45) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL482827 0.94 TDP1 (0.46) FAAHZDHHC7TDP1MEN1KMT2A
SCHEMBL650590 0.92 TDP1 (0.45) FAAHTDP1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0180745-A1 Acylacetate and amidine intermediates for pyrimidone compounds, and their preparation YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1986-05-14 EP claimed
CN-114456286-B Catalyst system for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-08-15 CN disclosed
CN-114456290-B Catalyst system for olefin polymerization and prepolymerized catalyst composition 中国石油化工股份有限公司 2023-07-21 CN disclosed
CN-114456290-A Catalyst system for olefin polymerization and prepolymerized catalyst composition 中国石油化工股份有限公司 2022-05-10 CN disclosed
CN-114456286-A Catalyst system for olefin polymerization and use thereof 中国石油化工股份有限公司 2022-05-10 CN disclosed
EP-1178031-B1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH MANGANESE CATALYSTS OR THE LIKE DAICEL CHEM (JP) 2012-02-01 EP disclosed
US-6548713-B2 Efficiently producing a compound having an alkyl group or alkenyl group bonded at the alpha position of an electron attractive group, by catalytic radical addition reaction with compound of Group 5,6,7,8, or 9 DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-15 US disclosed
US-20020165416-A1 Process for the preparation of organic compounds with manganese cataylsts or the like DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-07 US disclosed
US-6348617-B1 REACTING PYRUVIC ACID COMPOUND IN WATER WITH AMMONIUM OR ALKALI METAL BISULFITE TO GIVE AQUEOUS SOLUTION OF BISULFITE ADDUCT, ISOLATING BY PHASE SEPARATION, OPTIONALLY USING HYDROPHOBIC SOLVENT, CONTACTING WITH ACID TO DECOMPOSE ADDUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
EP-1178031-A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH MANGANESE CATALYSTS OR THE LIKE Daicel Chemical Industries, Ltd. (JP) 2002-02-06 EP disclosed
EP-0937703-A1 METHOD FOR PURIFYING PYRUVIC ACID COMPOUNDS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165416-A1 Process for the preparation of organic compounds with manganese cataylsts or the like SOD1, CAT, SOD3 FAAH 3968/4885ZDHHC7 1552/4885TDP1 4210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.