Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TLR3 | O15455 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4869775 | 1.00 | AKR1B1 (0.37) | AKR1B1ATMCACNA1CMAPTLMNA | |
| SCHEMBL4869825 | 1.00 | AKR1B1 (0.37) | AKR1B1ATMCACNA1CMAPTLMNA | |
| SCHEMBL4869785 | 1.00 | AKR1B1 (0.37) | AKR1B1ATMCACNA1CMAPTLMNA | |
| SCHEMBL4871424 | 1.00 | AKR1B1 (0.37) | AKR1B1ATMCACNA1CMAPTLMNA | |
| SCHEMBL2471965 | 0.87 | AKR1B1 (0.37) | AKR1B1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6985781 | 0.87 | AKR1B1 (0.37) | AKR1B1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL2472077 | 0.87 | AKR1B1 (0.37) | AKR1B1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL6985601 | 0.87 | AKR1B1 (0.37) | AKR1B1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL2473015 | 0.87 | AKR1B1 (0.37) | AKR1B1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL2475336 | 0.87 | AKR1B1 (0.37) | AKR1B1MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7420060-B2 | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them | SCHAEFFLER KG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20070093481-A1 | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093481-A1 | Benzopyran derivatives substituted with a thioxobenzoxazole derivative, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containingthem | TNNT2, TNNI3, BRIX1 | AKR1B1 3610/4885ATM 2499/4885CACNA1C 2598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.