Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871800 | 0.90 | CYP19A1 (0.59) | CHEK2TSHRCDC7LMNAGAA | |
| SCHEMBL4876408 | 0.88 | CASP3 (0.68) | CHEK2CASP3SENP8SENP7SENP6 | |
| SCHEMBL6441482 | 0.86 | CASP3 (0.62) | CHEK2CASP3SENP8SENP7SENP6 | |
| SCHEMBL14213702 | 0.82 | CASP3 (0.57) | CHEK2CASP3SENP8SENP7SENP6 | |
| SCHEMBL14904717 | 0.81 | CYP19A1 (0.69) | CASP3SENP8SENP7SENP6CDC7 | |
| SCHEMBL27609728 | 0.81 | CDC7 (0.50) | CASP3SENP8SENP7SENP6CDC7 | |
| Hydrochloric Acid SCHEMBL28572814 | 0.81 | CASP3 (0.56) | CHEK2CASP3SENP8SENP7SENP6 | |
| Hydrochloric Acid SCHEMBL28671716 | 0.81 | CASP3 (0.56) | CHEK2CASP3SENP8SENP7SENP6 | |
| SCHEMBL30344399 | 0.80 | CASP3 (0.77) | CHEK2CASP3SENP8SENP7SENP6 | |
| SCHEMBL5443742 | 0.80 | CASP3 (0.77) | CHEK2CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-20040180946-A1 | Phenyl-indole compounds for modulating IgE and inhibiting cellular proliferation | AVANIR PHARMACEUTICALS | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180946-A1 | Phenyl-indole compounds for modulating IgE and inhibiting cellular proliferation | IDO1, IDO2, CMA1 | CHEK2 3236/4885TSHR 3965/4885CASP3 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.