Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792596 | 0.88 | ABCC2 (0.33) | PIK3CDPIK3CAPIK3CBABCC2 | |
| SCHEMBL4874984 | 0.83 | ABCC2 (0.46) | ABCC2 | |
| SCHEMBL4791760 | 0.83 | BAZ2A (0.38) | — | |
| SCHEMBL4876224 | 0.78 | PIK3CA (0.42) | PIK3CA | |
| SCHEMBL4878828 | 0.76 | PARP1 (0.44) | ABCC2 | |
| Hydrochloric Acid SCHEMBL4790235 | 0.72 | TP53 (0.39) | — | |
| SCHEMBL4868542 | 0.70 | HRH3 (0.38) | PIK3CA | |
| SCHEMBL3280848 | 0.69 | ABCC2 (0.55) | ABCC2 | |
| SCHEMBL13787617 | 0.68 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16404868 | 0.67 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312211-A1 | Antibacterial Pyrrolopyridines, Pyrrolopyrimidines and Pyrroloazepines-154 | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312211-A1 | Antibacterial Pyrrolopyridines, Pyrrolopyrimidines and Pyrroloazepines-154 | SDHA, QDPR, PNKP | PIK3CD 465/4885PIK3CA 494/4885PIK3CB 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.