Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602275 | 0.82 | DPP4 (0.41) | ADORA2BALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10727327 | 0.82 | TLR7 (0.36) | ALDH1A1PDE4BPDE4DTDP1PDE4A | |
| SCHEMBL9602609 | 0.80 | HTT (0.51) | ALDH1A1ADORA2AHTTKMT2A | |
| SCHEMBL10588936 | 0.80 | ALDH1A1 (0.41) | HPGDALDH1A1PDE4BPDE4DTDP1 | |
| SCHEMBL3192664 | 0.79 | TLR7 (0.47) | HPGDALDH1A1PDE4BPDE4DTDP1 | |
| SCHEMBL30601125 | 0.79 | TLR7 (0.47) | HPGDALDH1A1PDE4BPDE4DTDP1 | |
| SCHEMBL1335102 | 0.79 | CSNK2A2 (0.37) | HTTKMT2AKDM4ENPSR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3198630 | 0.78 | TLR7 (0.46) | HPGDALDH1A1PDE4BPDE4DTDP1 | |
| SCHEMBL10587329 | 0.78 | NR1I2 (0.41) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9601900 | 0.78 | NR1I2 (0.41) | HPGDALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966205-A2 | PREPARATION OF 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINES VIA 1H-IMIDAZO[4,5-C]QUINOLIN-4-PHTHALIMIDE INTERMEDIATES | Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság (HU) | 2008-09-10 | — | — | EP | disclosed |
| US-20080103310-A1 | Preparation of 1H-imidazo[4,5-c]quinolin-4-amines via 1H-imidazo[4, 5-c]quinolin-4-phtalimide intermediates | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2008-05-01 | — | — | US | disclosed |
| WO-2008048683-A2 | PREPARATION OF 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINES VIA 1H-IMIDAZO[4,5-C]QUINOLIN-4-PHTHALIMIDE INTERMEDIATES | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103310-A1 | Preparation of 1H-imidazo[4,5-c]quinolin-4-amines via 1H-imidazo[4, 5-c]quinolin-4-phtalimide intermediates | AAAS, AZI2, PNMT | ADORA2B 572/4885HPGD 2110/4885ALDH1A1 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.