Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335102 | 0.91 | CSNK2A2 (0.37) | DPP4DPP8LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL10727327 | 0.86 | TLR7 (0.36) | RAB9ATDP1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9603139 | 0.84 | POLB (0.40) | LMNACYP1A2SMN1; SMN2KMT2APOLB | |
| SCHEMBL9602609 | 0.83 | HTT (0.51) | KMT2ALTA4HALDH1A1 | |
| SCHEMBL10588936 | 0.83 | ALDH1A1 (0.41) | RAB9ATDP1LMNAMEN1KMT2A | |
| SCHEMBL10739313 | 0.83 | TLR7 (0.49) | TDP1LMNAMEN1KMT2APOLB | |
| SCHEMBL4870104 | 0.82 | ADORA2B (0.36) | RAB9ATDP1LMNAADORA2BCYP1A2 | |
| SCHEMBL30601125 | 0.82 | TLR7 (0.47) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3192664 | 0.82 | TLR7 (0.47) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10587329 | 0.81 | NR1I2 (0.41) | RAB9ASMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-B1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1993-01-13 | — | — | EP | disclosed |