SCHEMBL4870452

SCHEMBL4870452

Cc1cc(O)ccc1N.Cc1cc(O)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.61
ALDH1A1 P00352 4/20 0.61
TDP1 Q9NUW8 3/20 0.61
ALOX15 P16050 2/20 0.61
THRB P10828 1/20 0.61
RECQL P46063 1/20 0.61
HIF1A Q16665 1/20 0.61
TSHR P16473 2/20 0.56
ESR2 Q92731 6/20 0.47
ESR1 P03372 6/20 0.47
AR P10275 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CHRM1 P11229 1/20 0.46
MAOA P21397 1/20 0.46
TBXA2R P21731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34069 1.00
SCHEMBL29357630 1.00
Methane SCHEMBL27914972 0.97 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1ALOX15THRB
Hydrochloric Acid SCHEMBL4653710 0.97 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1ALOX15THRB
SCHEMBL4732895 0.97 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1ALOX15THRB
Hydrochloric Acid SCHEMBL29836028 0.97 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1ALOX15THRB
Bromide SCHEMBL11087469 0.97 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1ALOX15THRB
Hydrochloric Acid SCHEMBL22061862 0.95 CYP3A4 (0.57) CYP3A4ALDH1A1TDP1ALOX15THRB
Methoxymethane SCHEMBL14813462 0.93 CYP3A4 (0.55) CYP3A4ALDH1A1TDP1ALOX15THRB
4-Aminophenol SCHEMBL27512906 0.91 ALDH1A1 (0.58) CYP3A4ALDH1A1TDP1ALOX15THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7431742-B2 Hair coloring kits and methods of use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-10-07 US disclosed
US-20070251025-A1 Hair coloring kits and methods of use thereof THE PROCTER & GAMBLE COMPANY 2007-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070251025-A1 Hair coloring kits and methods of use thereof COXFA4L2, SQOR, GPX4 CYP3A4 532/4885ALDH1A1 175/4885TDP1 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.