Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Methyl Pyrrolidine (Nmp) SCHEMBL25255705 | 0.79 | KDM4E (0.33) | KDM4E | |
| Ether SCHEMBL3979757 | 0.79 | TSHR (0.42) | TSHRMAPK1SMN1; SMN2KMT2AMEN1 | |
| Oxirane SCHEMBL4628850 | 0.78 | TSHR (0.33) | TSHRKMT2AMEN1GAA | |
| Tetrahydrofuran SCHEMBL28237450 | 0.77 | ALDH1A1 (0.42) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| Butane SCHEMBL28166789 | 0.76 | MAPK1 (0.38) | TSHRMAPK1SMN1; SMN2KMT2AMEN1 | |
| Butane SCHEMBL28257686 | 0.76 | MAPK1 (0.38) | TSHRMAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4622 | 0.75 | — | — | |
| SCHEMBL1221354 | 0.75 | — | — | |
| SCHEMBL20614479 | 0.75 | CA12 (0.45) | TSHRSMN1; SMN2ALDH1A1HPGDNPSR1 | |
| SCHEMBL10001930 | 0.75 | CA12 (0.45) | TSHRSMN1; SMN2ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215227-B1 | OXIDATIVE HAIR DYE COMPOSITION COMPRISING A COMBINATION OF CROSS LINKED AMINATED SILOXANPOLYMERS AND NON IONIC TENSIDS | HENKEL AG & CO KGAA (DE) | 2019-03-13 | — | — | EP | claimed |
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | claimed |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | HENKEL AG & CO. KGAA (DE) | 2017-08-17 | — | — | US | claimed |
| WO-2024134121-A1 | METHOD FOR CONTROLLING THE CROSSLINKING TIME FOR A SILICONE GEL THAT GIVES OFF A VOLATILE ORGANIC SUBSTANCE | V. MANE FILS (FR) | 2024-06-27 | — | — | WO | disclosed |
| CN-115397891-B | Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups | 瓦克化学股份公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230391802-A1 | PROCESS FOR SYNTHESIZING ALKOXY GROUP-CONTAINING AMINOSILOXANES | WACKER CHEMIE AG (DE) | 2023-12-07 | — | — | US | disclosed |
| US-20230374224-A1 | AQUEOUS DISPERSIONS OF AMINO-FUNCTIONALIZED ORGANOPOLYSILOXANES PRE-CROSSLINKED WITH OXALATOPOLYETHERS | WACKER CHEMIE AG (DE) | 2023-11-23 | — | — | US | disclosed |
| EP-4175962-B1 | PROCESS FOR SYNTHESIZING ALKOXY GROUP-CONTAINING AMINOSILOXANES | WACKER CHEMIE AG (DE) | 2023-10-18 | — | — | EP | disclosed |
| US-20230167246-A1 | Polysiloxanes with radiation- and moisture-cross-linkable groups | WACKER CHEMIE AG (DE) | 2023-06-01 | — | — | US | disclosed |
| EP-4136137-A1 | POLYSILOXANES WITH RADIATION- AND MOISTURE-CROSS-LINKABLE GROUPS | Wacker Chemie AG (DE) | 2023-02-22 | — | — | EP | disclosed |
| CN-111315826-B | Crosslinked aminosilicone polymers, method for the production and use thereof | 美国陶氏有机硅公司 | 2022-06-21 | — | — | CN | disclosed |
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | disclosed |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | HENKEL AG & CO. KGAA (DE) | 2017-08-17 | — | — | US | disclosed |
| US-9539199-B2 | Cosmetic compositions | WACKER CHEMIE AG (DE) | 2017-01-10 | — | — | US | disclosed |
| US-20140161756-A1 | COSMETIC COMPOSITIONS | WACKER CHEMIE AG (DE) | 2014-06-12 | — | — | US | disclosed |
| US-8304023-B2 | coating with a condensation-curable organopolysiloxanes with silanes to form elastomeric films insoluble in toluene; formed layer has a permanent soft hand and good bulk, no yellowing, free of volatile organic compounds; storage stability, solvent-free | WACKER CHEMIE AG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080107815-A1 | Preparation Of Aqueous Dispersions Of Organopolysiloxanes | WACKER CHEMIE AG (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080107814-A1 | Treatment Of Fiberfill Fibers With Aqueous Dispersions Of Organopolysiloxanes | WACKER CHEMIE AG (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080064813-A1 | METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS | WACKER CHEMIE AG (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20060258820-A1 | Process for preparing dispersions of crosslinked organopolysiloxanes | WACKER CHEMIE AG (DE) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140161756-A1 | COSMETIC COMPOSITIONS | H1-0, H1-2, H1-4 | TSHR 904/4885MAPK1 767/4885SMN1; SMN2 2305/4885 |
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | KRT18, PLOD3, SORD | TSHR 4320/4885MAPK1 1744/4885SMN1; SMN2 4023/4885 |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | KRT18, PLOD3, SORD | TSHR 4320/4885MAPK1 1744/4885SMN1; SMN2 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.