SCHEMBL4870534

SCHEMBL4870534

CC1(C)CC(CCCCCN)CC(C)(C)N1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.45
TSHR P16473 3/20 0.33
DNM1 Q05193 8/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA3 P07451 2/20 0.32
CA4 P22748 2/20 0.32
CA6 P23280 2/20 0.32
CA5A P35218 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA5B Q9Y2D0 2/20 0.32
LMNA P02545 1/20 0.32
BLM P54132 1/20 0.32
GAA P10253 1/20 0.32
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98369 0.98 SIGMAR1 (0.42) SIGMAR1TSHRGAAGRIN2DGRIN3B
SCHEMBL818726 0.89 TSHR (0.36) SIGMAR1TSHRLMNAGAA
SCHEMBL10621109 0.89 TSHR (0.36) SIGMAR1TSHRLMNAGAA
SCHEMBL28159382 0.89 TSHR (0.36) SIGMAR1TSHRLMNAGAA
SCHEMBL3961646 0.83 TSHR (0.36) TSHRLMNAGAA
SCHEMBL15707671 0.82 ALDH1A1 (0.39) TSHRGAAALDH1A1EPHX1
SCHEMBL15569964 0.82 ALDH1A1 (0.39) TSHRGAAALDH1A1EPHX1
SCHEMBL15570217 0.82 ALDH1A1 (0.39) TSHRGAAALDH1A1EPHX1
SCHEMBL16912862 0.82 ALDH1A1 (0.39) TSHRGAAALDH1A1EPHX1
SCHEMBL16912864 0.82 ALDH1A1 (0.39) TSHRGAAALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062270-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 2000-12-27 EP claimed
WO-1999046323-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 1999-09-16 WO claimed
US-7332535-B2 Stabilizer mixtures for the protection of polymer substrates CLARIANT FINANCE (BVI) LIMITED (VG) 2008-02-19 US disclosed
EP-1529075-B1 STABILIZER MIXTURES FOR THE PROTECTION OF POLYMER SUBSTRATES CLARIANT FINANCE BVI LTD (VG) 2007-11-07 EP disclosed
US-20060226395-A1 Stabilizer mixtures for the protection of polymer substrates CLARIANT INTERNATIONAL LTD. 2006-10-12 US disclosed
US-7081213-B2 Stabilizer mixtures for the protection of polymer substrates CLARIANT FINANCE (BVI) LIMITED (VG) 2006-07-25 US disclosed
US-20030234386-A1 Stabilizer mixtures for the protection of polymer substrates CLARIANT INTERNATIONAL, LTD. 2003-12-25 US disclosed
EP-1062270-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 2000-12-27 EP disclosed
WO-1999046323-A1 LIGHT AND THERMALLY STABLE POLYAMIDE BASF CORPORATION (US) 1999-09-16 WO disclosed