SCHEMBL664987

SCHEMBL664987

C[C@H](S)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL664500 1.00
SCHEMBL184638 1.00
Bromide SCHEMBL6735763 0.97 TAAR1 (0.44)
SCHEMBL28751595 0.87 TSHR (0.48)
SCHEMBL3174147 0.84 PTGS2 (0.54)
SCHEMBL332099 0.83 ESR1 (0.38)
SCHEMBL332300 0.79 HDAC4 (0.37)
SCHEMBL20216133 0.78 LTA4H (0.52)
SCHEMBL21524731 0.78 ALDH1A1 (0.46)
SCHEMBL1960097 0.77 TAAR1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198029-A1 INHIBITORS OF PEPTIDYL ARGININE DEIMINASE (PAD) ENZYMES AND USES THEREOF University Health Network (CA) 2023-06-21 EP disclosed
WO-2020215267-A1 USE OF NTCP INHIBITORS IN PREVENTING AND TREATING HEPATOCARCINOGENESIS NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) 2020-10-29 WO disclosed
WO-2020194920-A1 THERMOSETTING EPOXY RESIN COMPOSITION, LAYERED SHEET FOR CIRCUIT BOARD, METAL-BASED CIRCUIT BOARD, AND POWER MODULE 日本発條株式会社 2020-10-01 WO disclosed
WO-2018182774-A1 HERBICIDE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2018-10-04 WO disclosed
US-9868729-B2 Inhibitors of protein kinases PORTOLA PHARMACEUTICALS, INC. (US) 2018-01-16 US disclosed
EP-3062150-A2 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2016-08-31 EP disclosed
US-20160070174-A1 PATTERN FORMING METHOD, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2016-03-10 US disclosed
EP-2391600-B1 INTERMEDIATES IN THE ENANTIOSELECTIVE SYNTHESIS OF 3-(AMINOMETHYL)-5-METHYL-HEXANOIC ACID PROVOST FELLOWS & SCHOLARS COLLEGE OF THE HOLY UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2016-01-06 EP disclosed
US-9223219-B2 Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition and resist film FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
US-8877423-B2 Actinic ray-sensitive or radiation-sensitive resin composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2014-11-04 US disclosed
EP-1385870-B1 PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS SCHERING CORP (US) 2010-03-17 EP disclosed
US-7585535-B2 Flavour and fragrance compositions GIVAUDAN SA (CH) 2009-09-08 US disclosed
EP-1392132-B1 FLAVOUR AND FRAGRANCE COMPOSITIONS GIVAUDAN SA (CH) 2009-07-29 EP disclosed
US-20040253362-A1 Flavour and fragrance compositions GIVAUDAN SA (CH) 2004-12-16 US disclosed
EP-1392132-A1 FLAVOUR AND FRAGRANCE COMPOSITIONS Givaudan SA (CH) 2004-03-03 EP disclosed
WO-2002098241-A1 FLAVOUR AND FRAGRANCE COMPOSITIONS GIVAUDAN SA (CH) 2002-12-12 WO disclosed
EP-1264547-A1 Flavour and fragrance compositions Givaudan SA (CH) 2002-12-11 EP disclosed
EP-0083335-B1 OPTICALLY ACTIVE CHIRAL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE OF THESE COMPOUNDS IN THE PROTECTION OF FUNCTIONAL -OH, -SH, -NH- GROUPS, IN THE SEPARATION OF RACEMATES, IN THE PREPARATION OF OPTICALLY ACTIVE IMIDOESTER HYDROCHLORIDES AND OF OPTICALLY ACTIVE ESTERS, IN THE PREPARATION OF OPTICALLY ENRICHED ALCOHOLS AND IN THE PREPARATION OF OPTICALLY ACTIVE COMPOUNDS BY ASYMMETRIC INDUCTION Noe, Christian, Dipl.-Ing. Dr. (AT) 1987-08-12 EP disclosed
US-4497960-A Chiral, optically active compounds useful as protective groups for hydroxy, thiol and amino compounds NOE CHRISTIAN (AT) 1985-02-05 US disclosed
EP-0083335-A1 Optically active chiral compounds, process for their preparation and use of these compounds in the protection of functional -OH, -SH, -NH- groups, in the separation of racemates, in the preparation of optically active imidoester hydrochlorides and of optically active esters, in the preparation of optically enriched alcohols and in the preparation of optically active compounds by asymmetric induction Noe, Christian, Dipl.-Ing. Dr. (AT) 1983-07-06 EP disclosed