SCHEMBL4870935

SCHEMBL4870935

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COC=O)C(O)C1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 4/20 0.72
ADORA1 P30542 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
P2RY2 P41231 3/20 0.72
SRC P12931 2/20 0.72
TRPM2 O94759 2/20 0.72
TAS1R3 Q7RTX0 2/20 0.72
TAS1R1 Q7RTX1 2/20 0.72
DNPH1 O43598 1/20 0.72
PRKAB2 O43741 1/20 0.72
LDHA P00338 1/20 0.72
ADRB2 P07550 1/20 0.72
FBP1 P09467 1/20 0.72
PRKAG1 P54619 1/20 0.72
PRKAA2 P54646 1/20 0.72
PDE4D Q08499 1/20 0.72
KCNH2 Q12809 1/20 0.72
PRKAA1 Q13131 1/20 0.72
PDE3A Q14432 1/20 0.72
P2RY11 Q96G91 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582406 1.00 P2RY1 (0.72) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL1934658 0.89 AHCY (0.72) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL30760493 0.88 P2RY1 (0.56) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL8003533 0.87 ADORA1 (0.71) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL12963362 0.86 ADORA1 (0.76) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL2040670 0.86 ADORA1 (0.76) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL7803298 0.86 ADORA1 (0.76) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL5024895 0.86 ADORA1 (0.76) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL481524 0.86 ADORA1 (0.76) P2RY1ADORA1SMN1; SMN2P2RY2SRC
SCHEMBL10997946 0.86 ADORA1 (0.76) P2RY1ADORA1SMN1; SMN2P2RY2SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104062334-A Quantitative analysis method aiming at DNA methylation monitoring UNIV FUZHOU 2014-09-24 CN claimed
US-11685923-B2 Methods of enhancing translation ability of RNA molecules, treatments, and kits CORNELL UNIVERSITY (US) 2023-06-27 US disclosed
EP-4010473-A1 COMPOSITIONS AND METHODS FOR DETECTING METHYLATED DNA Battelle Memorial Institute (US) 2022-06-15 EP disclosed
US-20220170013-A1 T:A TO A:T BASE EDITING THROUGH ADENOSINE METHYLATION THE BROAD INSTITUTE, INC. (US) 2022-06-02 US disclosed
US-11066653-B2 Method of transforming bacterial cells BASF SE (DE) 2021-07-20 US disclosed
WO-2021030194-A1 COMPOSITIONS AND METHODS FOR DETECTING METHYLATED DNA SPURBECK RACHEL R (US) 2021-02-18 WO disclosed
US-20200199601-A1 METHODS OF ENHANCING TRANSLATION ABILITY OF RNA MOLECULES, TREATMENTS, AND KITS UNIV CORNELL (US) 2020-06-25 US disclosed
US-20200165581-A1 METHOD OF TRANSFORMING BACTERIAL CELLS BASF SE (DE) 2020-05-28 US disclosed
EP-3655528-A1 METHOD OF TRANSFORMING BACTERIAL CELLS BASF SE (DE) 2020-05-27 EP disclosed
US-10584343-B2 Methods of enhancing translation ability of RNA molecules, treatments, and kits CORNELL UNIVERSITY (US) 2020-03-10 US disclosed
CN-107400711-A Use the cell filtration small nucleic acids being permeabilized 伯乐实验室公司 2017-11-28 CN disclosed
WO-2017011766-A1 METHODS OF ENHANCING TRANSLATION ABILITY OF RNA MOLECULES TREATMENTS, AND KITS CORNELL UNIVERSITY (US) 2017-01-19 WO disclosed
CN-104062334-A Quantitative analysis method aiming at DNA methylation monitoring UNIV FUZHOU 2014-09-24 CN disclosed
US-7345229-B1 Insect resistant cotton plants DOW AGROSCIENCES LLC (US) 2008-03-18 US disclosed
US-6943282-B1 Insect resistant plants MYCOGEN PLANT SCIENCE, INC. (US) 2005-09-13 US disclosed
US-20030129709-A1 Method for site-directed mutagenesis of nucleic acid molecules using a single primer MAKAROVA OLGA (US) 2003-07-10 US disclosed
WO-2003040376-A1 METHOD FOR SITE-DIRECTED MUTAGENESIS OF NUCLEIC ACID MOLECULES USING A SINGLE PRIMER MAKAROVA OLGA (US) 2003-05-15 WO disclosed
US-5578702-A TRUNCATED BACILLUS THURINGIENSIS DELTA-ENDOTOXIN MYCOGEN PLANT SCIENCE, INC. (US) 1996-11-26 US disclosed
EP-0142924-B1 INSECT RESISTANT PLANTS Mycogen Plant Science, Inc. (US) 1992-04-15 EP disclosed
EP-0142924-A2 Insect resistant plants Mycogen Plant Science, Inc. (US) 1985-05-29 EP disclosed