Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.71 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.70 |
| ▸ | SRC | P12931 | 2/20 | 0.70 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.70 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.70 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.70 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | FBP1 | P09467 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.70 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944751 | 0.90 | AHCY (0.69) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL8328542 | 0.88 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL4870935 | 0.87 | P2RY1 (0.72) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL8582406 | 0.87 | P2RY1 (0.72) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL3302567 | 0.87 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL4916792 | 0.87 | ADORA1 (0.65) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL3306997 | 0.86 | ADORA1 (0.66) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL873362 | 0.86 | ADORA3 (0.72) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL3698839 | 0.86 | ADORA3 (0.72) | ADORA1ADORA3ADORA2AADORA2BP2RY1 | |
| SCHEMBL6026018 | 0.85 | P2RY1 (0.70) | ADORA1ADORA3ADORA2AADORA2BP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008214-A1 | OLIGONUCLEOTIDE ANALOGS HAVING MODIFIED DIMERS | ISIS PHARMACEUTICALS, INC. (US) | 2000-02-17 | — | — | WO | disclosed |