Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424516 | 0.83 | GPR35 (0.56) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL3172874 | 0.83 | GPR35 (0.56) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL25193049 | 0.82 | MEN1 (0.62) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL205059 | 0.81 | MEN1 (1.00) | HTTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL12095462 | 0.79 | MEN1 (0.95) | HTTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL25183609 | 0.79 | HTT (0.57) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL25194959 | 0.77 | HTT (0.64) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL27787884 | 0.77 | HTT (0.64) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL27787752 | 0.76 | MEN1 (0.62) | HTTMEN1KMT2ALMNAPOLB | |
| SCHEMBL25188260 | 0.76 | HTT (0.62) | HTTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997803-B1 | A TECHNIQUE FOR MODIFICATION OF A BIO-PRODUCT MOLECULE AND APPLICATION OF WEED CONTROL | UNIV NANJING AGRICULTURAL (CN) | 2018-02-14 | — | — | EP | disclosed |
| CN-103922990-B | A kind of molecular modification of Natural occurring compounds and the method for weeding | 南京农业大学 | 2017-11-07 | — | — | CN | disclosed |
| US-9468209-B2 | Method for eradicating weeds with derivatives of 3-acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one | NANJING AGRICULTURAL UNIVERSITY (CN) | 2016-10-18 | — | — | US | disclosed |
| US-20150141254-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | NANJING AGRICULTURAL UNIVERSITY (CN) | 2015-05-21 | — | — | US | disclosed |
| US-8921274-B2 | Method for eradicating weeds with derivatives of 3-acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one | NANJING AGRICULTURAL UNIVERSITY (CN) | 2014-12-30 | — | — | US | disclosed |
| CN-103922990-A | Method for molecular modification and weed control of biological source compound | UNIV NANJING AGRICULTURAL | 2014-07-16 | — | — | CN | disclosed |
| US-20120172226-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | Nantong Jiangshan Agrochemical & Cheimcal Limited Liability Co., Ltd. (CN) | 2012-07-05 | — | — | US | disclosed |
| EP-1997803-A1 | A TECHNIQUE FOR MODIFICATION OF A BIO-PRODUCT MOLECULE AND APPLICATION OF WEED CONTROL | Nanjing Agricultural University (CN) | 2008-12-03 | — | — | EP | disclosed |
| US-20080176748-A1 | derived from 3-acetyl-4-hydroxy-5-sec-butylpyrroline-2-ketone, a natural substance, and their potential use in agriculture for weed control | NANJING AGRICULTURAL UNIVERSITY (CN) | 2008-07-24 | — | — | US | disclosed |
| CN-101228124-A | Molecular modification of biological source compound and method for weeding | UNIV NANJING AGRICULTURAL (CN) | 2008-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172226-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | NOTUM, PGA5, ALG1 | HTT 2191/4885MEN1 4041/4885KMT2A 4258/4885 |
| US-20080176748-A1 | derived from 3-acetyl-4-hydroxy-5-sec-butylpyrroline-2-ketone, a natural substance, and their potential use in agriculture for weed control | HADH, HADHB, ABAT | HTT 839/4885MEN1 4881/4885KMT2A 1533/4885 |
| US-20150141254-A1 | METHOD FOR ERADICATING WEEDS WITH DERIVATIVES OF 3-ACETYL-5-SEC-BUTYL-4-HYDROXY-3-PYRROLIN-2-ONE | NOTUM, HDAC6, PGA5 | HTT 2081/4885MEN1 3692/4885KMT2A 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.