SCHEMBL4871845

SCHEMBL4871845

C=CCc1cccc(O)c1C(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.50
GABRB2 P47870 3/20 0.50
AKR1B1 P15121 1/20 0.43
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
ALDH1A1 P00352 4/20 0.40
GAA P10253 3/20 0.40
MAPT P10636 3/20 0.40
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 2/20 0.40
CASP1 P29466 1/20 0.40
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MAPK1 P28482 1/20 0.38
POLB P06746 1/20 0.37
CA2 P00918 1/20 0.36
LMNA P02545 2/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2054348 0.84 GABRA1 (0.47) GABRA1GABRB2AKR1B1KMT2AMEN1
2-Allylphenol SCHEMBL9516154 0.80 CA2 (0.53) GABRA1GABRB2AKR1B1KMT2AMEN1
2-Allylphenol SCHEMBL10901820 0.79 TSHR (0.60) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL29475280 0.79 HSPA5 (0.50) GABRA1GABRB2AKR1B1ALDH1A1HSD17B10
SCHEMBL1980875 0.79 GABRA1 (0.59) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL16147388 0.78 GABRA1 (0.46) GABRA1GABRB2AKR1B1KMT2AMEN1
SCHEMBL6407131 0.77 GABRA1 (0.58) GABRA1GABRB2AKR1B1ALDH1A1TSHR
SCHEMBL10715136 0.77 GABRA1 (0.41) GABRA1GABRB2KMT2AMEN1ALDH1A1
SCHEMBL10413004 0.76 GABRA1 (0.43) GABRA1GABRB2AKR1B1GAAPOLB
SCHEMBL5571089 0.76 GABRA1 (0.43) GABRA1GABRB2AKR1B1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470292-B2 Mannich base derived from p-substituted phenols or cashew nut shell oil and aromatic diamine; sedimentation, corrosion and water uptake resistance INDIAN OIL CORPORATION LIMITED (IN) 2008-12-30 US disclosed
US-20050091914-A1 Antioxidant composition for motor gasoline INDIAN OIL CORPORATION LIMITED (IN) 2005-05-05 US disclosed
EP-0696635-B1 Two-stroke engine lubricant and method of using same LUBRIZOL CORP (US) 2001-12-12 EP disclosed
EP-0624639-B1 Fuel composition LUBRIZOL CORP (US) 1998-08-12 EP disclosed
US-5723694-A REACTION OF FORMALDEHYDE WITH PHENOL AND CATALYTIC HYDROGENATION BAYER AKTIENGESELLSCHAFT (DE) 1998-03-03 US disclosed
US-5560755-A PROVIDES FUEL INTAKE SYSTEM CLEANLINESS IN PORT FUEL INJECTED INTERNAL COMBUSTION ENGINE THE LUBRIZOL CORPORATION (US) 1996-10-01 US disclosed
EP-0696635-A2 Two-stroke engine lubricant and method of using same THE LUBRIZOL CORPORATION (US) 1996-02-14 EP disclosed
US-5458793-A Compositions useful as additives for lubricants and liquid fuels THE LUBRIZOL CORPORATION (US) 1995-10-17 US disclosed
US-5441653-A Two-stroke cycle engine lubricant and method of using same THE LUBRIZOL CORPORATION (US) 1995-08-15 US disclosed
EP-0624638-A1 Compositions useful as additives for lubricants and liquid fuels The Lubrizol Corporation (US) 1994-11-17 EP disclosed
EP-0624639-A1 Fuel composition The Lubrizol Corporation (US) 1994-11-17 EP disclosed
US-5336278-A Fuel composition containing an aromatic amide detergent THE LUBRIZOL CORPORATION (US) 1994-08-09 US disclosed