2-Allylphenol

2-Allylphenol

SCHEMBL9516154

C=CCc1ccccc1O.CC(C)(C)c1cccc(C(C)(C)C)c1O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.53
GABRA1 P14867 3/20 0.49
GABRB2 P47870 3/20 0.49
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
AKR1B1 P15121 1/20 0.46
ALOX12 P18054 1/20 0.41
ATM Q13315 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GAA P10253 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CASP1 P29466 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPK1 P28482 1/20 0.38
HSPA5 P11021 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Allylphenol SCHEMBL10901820 0.90 TSHR (0.60) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1980875 0.87 GABRA1 (0.59) CA2GABRA1GABRB2ALDH1A1TSHR
Butylated Hydroxytoluene SCHEMBL1889653 0.87 CA2 (0.51) CA2GABRA1GABRB2ALDH1A1TSHR
2-Allylphenol SCHEMBL28195855 0.81 GABRA1 (0.41) GABRA1GABRB2ALDH1A1TSHRTDP1
2-Allylphenol SCHEMBL565880 0.81 GABRA1 (0.53) CA2GABRA1GABRB2ALDH1A1TSHR
2-Allylphenol SCHEMBL29272030 0.81 GABRA1 (0.53) CA2GABRA1GABRB2ALDH1A1TSHR
2-Allylphenol SCHEMBL27508196 0.81 GABRA1 (0.53) CA2GABRA1GABRB2ALDH1A1TSHR
2-Allylphenol SCHEMBL29381085 0.81 GABRA1 (0.57) CA2GABRA1GABRB2TSHRAKR1B1
2-Allylphenol SCHEMBL31591833 0.81 GABRA1 (0.57) CA2GABRA1GABRB2TSHRAKR1B1
2-Allylphenol SCHEMBL160157 0.81 GABRA1 (0.57) CA2GABRA1GABRB2TSHRAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5155868-A None JP disclosed