SCHEMBL4871912

SCHEMBL4871912

C=C(C)C(=O)NCO.C=CC(=O)NCO

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
TGFBR1 P36897 1/20 0.36
TGM2 P21980 2/20 0.33
GAA P10253 1/20 0.33
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8517040 0.91 TSHR (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL11208764 0.89 TSHR (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
Methacrylic Acid SCHEMBL4373665 0.86 ALDH1A1 (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acrylic Acid SCHEMBL27397347 0.86 ALOX15 (0.42) TSHRALDH1A1MAPK1TDP1TGFBR1
SCHEMBL15271275 0.85 TGFBR1 (0.39) TSHRALDH1A1MAPK1TDP1TGFBR1
Acetone SCHEMBL9190129 0.85 ALDH1A1 (0.56) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27050 0.85
Acrylamide SCHEMBL20357508 0.84 ALDH1A1 (0.44) TSHRALDH1A1MAPK1TDP1TGFBR1
SCHEMBL2191231 0.84 TDP1 (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acetic Acid SCHEMBL4650595 0.83 ALDH1A1 (0.54) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9416300-B2 Low temperature curable adhesive compositions SIMPSON STRONG-TIE COMPANY, INC. (US) 2016-08-16 US claimed
EP-0421787-A2 Method of coating a substrate with an ambient temperature-drying aqueous elastomeric composition ROHM AND HAAS COMPANY (US) 1991-04-10 EP claimed
US-11072840-B2 Use of hydrophobically associating copolymers as binders for pelletizing metal containing ores BASF SE (DE) 2021-07-27 US disclosed
US-20200407820-A1 USE OF COPOLYMERS AS BINDERS FOR PELLETIZING METAL CONTAINING ORES BASF SE (DE) 2020-12-31 US disclosed
US-20190010577-A1 USE OF HYDROPHOBICALLY ASSOCIATING COPOLYMERS AS BINDERS FOR PELLETIZING METAL CONTAINING ORES BASF SE (DE) 2019-01-10 US disclosed
US-7402626-B2 Top coat composition CENTRAL GLASS COMPANY, LIMITED (JP) 2008-07-22 US disclosed
WO-1998020048-A2 METHOD FOR PRODUCING LOW VISCOSITY AQUEOUS POLYMER DISPERSIONS WITH POLYMODAL DISTRIBUTION OF POLYMER PARTICLE SIZE BASF AKTIENGESELLSCHAFT (DE) 1998-05-14 WO disclosed
EP-0430220-B1 Photosensitive resin composition and semiconductor apparatus using it SUMITOMO BAKELITE CO (JP) 1997-05-07 EP disclosed
US-5362613-A Silver halide photographic material having layers including light-sensitive silver halide emulsion layer on support and layer containing cationic high molecular weight compound with quaternized acrylic ester or amide units FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
EP-0430220-A2 Photosensitive resin composition and semiconductor apparatus using it SUMITOMO BAKELITE COMPANY LIMITED (JP) 1991-06-05 EP disclosed
EP-0150059-B1 METAL CONTAINER COATING COMPOSTIONS COMPRISING STABLE EMULSIONS OF WATER RESISTANT VINYL CHLORIDE-ETHYLENE COPOLYMERS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-08-02 EP disclosed