SCHEMBL4872017

SCHEMBL4872017

C=Cc1ccc(OC)cc1[SiH](C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 12/20 0.44
CYP1A1 P04798 11/20 0.44
CYP1B1 Q16678 11/20 0.44
ALDH1A1 P00352 5/20 0.42
TRIM24 O15164 1/20 0.41
TYR P14679 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
NFE2L2 Q16236 2/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
NQO2 P16083 1/20 0.39
RAB9A P51151 1/20 0.39
CYP3A4 P08684 3/20 0.38
CYP2C19 P33261 2/20 0.38
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4870800 0.81 NQO1 (0.42) CYP1A2ALDH1A1MEN1KMT2AKDM4E
SCHEMBL4874384 0.81 KIF11 (0.34)
SCHEMBL8759292 0.81
SCHEMBL4868385 0.81 KMT2A (0.40) ALDH1A1KMT2AKDM4EPOLBHPGD
SCHEMBL30567454 0.78 CYP1A2 (0.52) CYP1A2CYP1A1CYP1B1ALDH1A1TRIM24
SCHEMBL9065566 0.78 CYP1A2 (0.52) CYP1A2CYP1A1CYP1B1ALDH1A1TRIM24
SCHEMBL30411244 0.75 CYP1A2 (0.70) CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2
SCHEMBL1130309 0.75 CYP1A2 (0.48) CYP1A2CYP1A1CYP1B1ALDH1A1TRIM24
SCHEMBL11425918 0.75
SCHEMBL3627239 0.75 CYP1A2 (0.70) CYP1A2CYP1A1CYP1B1ALDH1A1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US claimed
US-7368514-B2 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-05-06 US disclosed
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US disclosed