SCHEMBL4868385

SCHEMBL4868385

C=Cc1ccc(OC(C)C)cc1[SiH](C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 4/20 0.38
ALDH1A3 P47895 1/20 0.37
PARP10 Q53GL7 1/20 0.35
BRD4 O60885 1/20 0.35
BRPF1 P55201 1/20 0.35
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.34
MDM2 Q00987 2/20 0.34
KDM4E B2RXH2 2/20 0.33
FGFR1 P11362 1/20 0.33
POLB P06746 1/20 0.33
CBFB Q13951 1/20 0.33
MCL1 Q07820 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
GLA P06280 1/20 0.33
HTT P42858 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4872017 0.81 CYP1A2 (0.44) KMT2AALDH1A1KDM4EPOLBHPGD
SCHEMBL12885258 0.77 ALDH1A1 (0.41) KMT2AALDH1A1ALDH1A3PARP10BRD4
SCHEMBL4874384 0.77 KIF11 (0.34)
SCHEMBL4870800 0.77 NQO1 (0.42) KMT2AALDH1A1KDM4EHTTHPGD
SCHEMBL8759292 0.77
SCHEMBL12885255 0.74 ALDH1A1 (0.41) KMT2AALDH1A1ALDH1A3PARP10BRD4
SCHEMBL6935704 0.74 ALDH1A1 (0.41) KMT2AALDH1A1ALDH1A3PARP10BRD4
SCHEMBL6932787 0.72 ALDH1A1 (0.40) KMT2AALDH1A1ALDH1A3PARP10BRD4
SCHEMBL9551462 0.72 ALDH1A1 (0.47) KMT2AALDH1A1PARP10BRD4BRPF1
SCHEMBL11425918 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US claimed
US-7368514-B2 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-05-06 US disclosed
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US disclosed