SCHEMBL4874384

SCHEMBL4874384

C=Cc1ccc(OC(C)(C)C)cc1[SiH](C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.34
SRD5A1 P18405 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4872017 0.81 CYP1A2 (0.44)
SCHEMBL3203388 0.77 KIF11 (0.37) KIF11SRD5A1
SCHEMBL3628375 0.77 KIF11 (0.37) KIF11SRD5A1
SCHEMBL4868385 0.77 KMT2A (0.40)
SCHEMBL8759292 0.77
SCHEMBL4870800 0.77 NQO1 (0.42)
SCHEMBL17921276 0.76 CYP1A1 (0.39) KIF11SRD5A1
SCHEMBL20224935 0.76 KIF11 (0.36) KIF11SRD5A1
SCHEMBL3690339 0.73 KIF11 (0.34) KIF11SRD5A1
SCHEMBL7709174 0.72 FBP1 (0.38) KIF11SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US claimed
US-7368514-B2 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-05-06 US disclosed
US-20050107561-A1 Siloxane monomer containing trifluorovinylether group and sol-gel hybrid polymer prepared by using the same GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-05-19 US disclosed