SCHEMBL4872263

SCHEMBL4872263

Nc1c(N=O)cnn1Cc1cccnc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
PKM P14618 1/20 0.56
TSHR P16473 1/20 0.43
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
ILK Q13418 1/20 0.41
CYP11B1 P15538 1/20 0.41
KDM4E B2RXH2 1/20 0.41
UBE2N P61088 1/20 0.41
ATM Q13315 1/20 0.41
P2RX7 Q99572 1/20 0.41
LMNA P02545 1/20 0.41
CHRNA7 P36544 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2B Q13224 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4875835 0.82 KDM4E (0.49) ALDH1A1PKMTSHRCYP11B1KDM4E
Hydrochloric Acid SCHEMBL6757438 0.82 TSHR (0.48) ALDH1A1PKMTSHRKDM4ELMNA
SCHEMBL16324823 0.81 ALDH1A1 (0.51) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL16324826 0.81 ALDH1A1 (0.51) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL13989341 0.80 ALDH1A1 (0.64) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL16325103 0.78 ALDH1A1 (0.48) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL16325105 0.78 ALDH1A1 (0.48) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL16324776 0.77 ALDH1A1 (0.47) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL16324777 0.77 ALDH1A1 (0.47) ALDH1A1PKMTSHRADORA2AADORA1
SCHEMBL16324257 0.74 ALDH1A1 (0.44) ALDH1A1PKMTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462204-B2 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds WELLA AG (DE) 2008-12-09 US disclosed
US-20070056120-A1 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2007-03-15 US disclosed
EP-1687280-A1 CATIONIC DIAMINOPYRAZOLES, A METHOD FOR THE PRODUCTION THEREOF AND DYES CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 2006-08-09 EP disclosed
WO-2005051918-A1 CATIONIC DIAMINOPYRAZOLES, A METHOD FOR THE PRODUCTION THEREOF AND DYES CONTAINING THESE COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2005-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070056120-A1 Cationic diaminopyrazoles, a process for producing them and colorants containing these compounds KRT18, DSP, TUBA4A ALDH1A1 978/4885PKM 463/4885TSHR 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.