SCHEMBL4872348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL390863	0.86	KMT2A (0.41)	MEN1KMT2AALDH1A1
	SCHEMBL390748	0.82	ALDH1A1 (0.44)	MEN1KMT2AALDH1A1
	SCHEMBL390783	0.82	ALDH1A1 (0.41)	MEN1KMT2AALDH1A1
	SCHEMBL1544893	0.81	ALDH1A1 (0.46)	MEN1KMT2AALDH1A1
	SCHEMBL28381052	0.81	MEN1 (0.30)	MEN1KMT2A
	SCHEMBL17725440	0.78	MEN1 (0.58)	MEN1KMT2AALDH1A1
	SCHEMBL18454281	0.76	MEN1 (0.35)	MEN1KMT2AHSD11B1ALDH1A1
	SCHEMBL17712727	0.75	MEN1 (0.64)	MEN1KMT2ADRD3DRD2KCNH2
	SCHEMBL19612578	0.75	DRD2 (0.35)	MEN1KMT2ADRD3DRD2KCNH2
	SCHEMBL22211357	0.73	PDE1B (0.35)	PDE1BMEN1KMT2ADRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.