Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882801 | 1.00 | TDP1 (0.53) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1173737 | 0.99 | TDP1 (0.51) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL4882782 | 0.93 | TSHR (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11018360 | 0.86 | TSHR (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL194750 | 0.86 | TSHR (0.58) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL10585165 | 0.85 | ALDH1A1 (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL11229934 | 0.84 | TSHR (0.66) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL4805293 | 0.84 | TSHR (0.66) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL9156195 | 0.83 | ALDH1A1 (0.69) | TDP1POLBTSHRALDH1A1LMNA | |
| SCHEMBL22289836 | 0.83 | ALDH1A1 (0.69) | TDP1POLBTSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182919-A1 | Dental Restorative Composition | SUN MEDICAL CO., LTD. (JP) | 2008-07-31 | — | — | US | disclosed |
| EP-1854447-A1 | DENTAL RESTORATION MATERIAL COMPOSITION | SUN MEDICAL CO., LTD. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182919-A1 | Dental Restorative Composition | PARG, PARN, FHIT | TDP1 312/4885POLB 269/4885APEX1 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.