SCHEMBL487278

SCHEMBL487278

CCCC1CCC[C]1CC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 4/20 0.38
NOS1 P29475 4/20 0.38
NOS2 P35228 4/20 0.38
PDE9A O76083 2/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CYP19A1 P11511 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487214 0.93 NOS1 (0.40) NOS3NOS1NOS2CA1CA2
SCHEMBL487346 0.91 NOS1 (0.42) NOS3NOS1NOS2CA1CA2
SCHEMBL487299 0.84 NOS3 (0.37) NOS3NOS1NOS2PDE9ACA1
SCHEMBL258283 0.81
SCHEMBL487148 0.78 NOS1 (0.39) NOS3NOS1NOS2CA1CA2
SCHEMBL487370 0.77 NOS1 (0.41) NOS3NOS1NOS2CA1CA2
SCHEMBL743607 0.74 NOS3 (0.41) NOS3NOS1NOS2CA1CA2
SCHEMBL198217 0.74 NOS3 (0.41) NOS3NOS1NOS2CA1CA2
SCHEMBL487110 0.74
SCHEMBL27525324 0.74 NOS1 (0.38) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451184-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2019-10-22 US disclosed
EP-2949783-B1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR (JP) 2019-10-09 EP disclosed
EP-1666573-B1 LOW-FRICTION SLIDING MECHANISM AND METHOD OF FRICTION REDUCTION NISSAN MOTOR (JP) 2019-05-15 EP disclosed
EP-1510692-B1 Refrigerant compressor and friction control process therefor NISSAN MOTOR (JP) 2018-02-21 EP disclosed
US-20170335964-A1 SLIDING MEMBER AND METHOD FOR PRODUCING SAME NISSAN MOTOR CO., LTD. (JP) 2017-11-23 US disclosed
US-9759323-B2 Sliding member and method for producing same NISSAN MOTOR CO., LTD. (JP) 2017-09-12 US disclosed
EP-1666572-B1 SYSTEM HAVING DLC CONTACTING FACES, METHOD FOR LUBRICATING THE SYSTEM AND LUBRICATING OIL FOR THE SYSTEM NIPPON OIL CORP (JP) 2017-05-17 EP disclosed
EP-1018538-B1 REFRIGERATOR FLUID COMPOSITION NIPPON MITSUBISHI OIL CORP (JP) 2017-03-22 EP disclosed
EP-2343355-B1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2016-12-07 EP disclosed
EP-2256181-B1 Lubricant base oil and lubricant composition for an internal combustion engine and lubricant composition for a driving force transmitting device NIPPON OIL CORP (JP) 2016-06-01 EP disclosed
EP-1122295-A1 GASOLINE ADDITIVE FOR DIRECT-INJECTION GASOLINE ENGINE Nippon Mitsubishi Oil Corporation (JP) 2001-08-08 EP disclosed
US-20010005957-A1 Fuel additive and fuel composition NIPPON MITSUBISHI OIL CORPORATION 2001-07-05 US disclosed
EP-1018538-A1 REFRIGERATOR OIL COMPOSITION AND REFRIGERATOR FLUID COMPOSITION Nippon Mitsubishi Oil Corporation (JP) 2000-07-12 EP disclosed
US-5928393-A ESTERIFIED, ALKOXYLATED TERTIARY AMINE COMPOUND; DETERGENT ANTISLUDGE/ANTIDEPOSIT AGENT FOR INTERNAL COMBUSTION ENGINES NIPPON OIL CO., LTD. (JP) 1999-07-27 US disclosed
EP-0905217-A1 Unleaded gasoline for direct injection gasoline engine NIPPON OIL CO. LTD. (JP) 1999-03-31 EP disclosed
US-5837016-A ETHERIFIED (POLY)OXYALKYLENE GLYCOL CONTAINING AN AMIDE GROUP; INTERNAL COMBUSTION ENGINE ANTIDEPOSIT AGENTS NIPPON OIL CO., LTD. (JP) 1998-11-17 US disclosed
US-5755833-A URETHANE COMPOUND; ANTIDEPOSIT, ANTISLUDGING AGENT; GASOLINE NIPPON OIL CO., LTD. (JP) 1998-05-26 US disclosed
EP-0819753-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1998-01-21 EP disclosed
EP-0801128-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1997-10-15 EP disclosed
EP-0723985-A1 Fuel additive NIPPON OIL CO. LTD. (JP) 1996-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010005957-A1 Fuel additive and fuel composition NOTUM, DEGS1, NDUFC1 NOS3 165/4885NOS1 35/4885NOS2 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.