Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | FPR1 | P21462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874955 | 0.86 | ENPP2 (0.66) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4870540 | 0.85 | ALDH1A1 (0.69) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29392969 | 0.85 | HTT (0.75) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4881088 | 0.82 | MAPT (0.73) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29835096 | 0.82 | HTT (0.74) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4881706 | 0.82 | TSHR (0.67) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29739754 | 0.81 | HTT (0.78) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4878775 | 0.80 | MAPT (0.76) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29563681 | 0.80 | HTT (0.74) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29739849 | 0.80 | HTT (0.77) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249154-A1 | Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-10-09 | — | — | US | disclosed |
| EP-1698335-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR DISEASE IN WHICH MITOCHONDRIAL BENZODIAZEPINE RECEPTOR PARTICIPATES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249154-A1 | Preventive and/or Therapeutic Agent For Disease In Which Mitochondrial Benzodiazephine Receptor Participates | MTNR1A, GSR, NLN | TSHR 214/4885CYP1A2 688/4885CYP3A4 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.