Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874493 | 0.81 | CYP2D6 (0.61) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL4870815 | 0.79 | CYP1A2 (0.62) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL4874899 | 0.77 | CYP2D6 (0.50) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL4870597 | 0.73 | CYP2D6 (0.50) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL14269705 | 0.72 | LMNA (0.45) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL4870075 | 0.70 | — | — | |
| SCHEMBL4864366 | 0.69 | — | — | |
| SCHEMBL10125332 | 0.69 | KCNA5 (0.76) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL8983627 | 0.68 | CYP2D6 (0.83) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL8983562 | 0.68 | CYP2D6 (0.83) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335781-B2 | Aminothiol compound | HUEY JIIN CO., LTD. (TW) | 2008-02-26 | — | — | US | disclosed |
| US-20040181057-A1 | perform as superior catalysts in asymmetric addition reactions wherein organic zinc and aldehyde are involved; Such catalyses are economically useful for industries | HUEY JIIN CO., LTD. (TW) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181057-A1 | perform as superior catalysts in asymmetric addition reactions wherein organic zinc and aldehyde are involved; Such catalyses are economically useful for industries | ALDH7A1, ALDH3A1, ALDH1A1 | CYP2D6 580/4885CYP1A2 303/4885CYP3A4 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.