SCHEMBL4873463

SCHEMBL4873463

O=C(O)Oc1ccc2c(OC(=O)O)c(OC(=O)O)ccc2c1OC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 4/20 0.32
MAPT P10636 3/20 0.32
HTT P42858 2/20 0.32
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.32
RECQL P46063 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 2/20 0.31
GAA P10253 2/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
HPGD P15428 2/20 0.31
MPI P34949 1/20 0.31
ABCB11 O95342 1/20 0.31
CFD P00746 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723622 0.98 MAPK1 (0.32) MAPK1KDM4EMAPTHTTLMNA
SCHEMBL9649492 0.88 ESR1 (0.44) MAPK1KDM4EMAPTHTTSMN1; SMN2
SCHEMBL1039198 0.87 MAPK1 (0.36) MAPK1KDM4EMAPTSMN1; SMN2TDP1
SCHEMBL8720840 0.84 NCEH1 (0.33) KDM4EALDH1A1GAATSHRRAB9A
SCHEMBL8746463 0.83 PIM1 (0.34) KDM4EMAPTTDP1ALDH1A1GAA
SCHEMBL7068984 0.80 NCEH1 (0.45) MAPK1KDM4EMAPTLMNASMN1; SMN2
SCHEMBL8721229 0.80 HTT (0.37) KDM4EMAPTHTTLMNASMN1; SMN2
SCHEMBL1551337 0.79 GABRP (0.33) MAPK1KDM4EHTTLMNAL3MBTL1
SCHEMBL9360148 0.78 KDM4E (0.35) MAPK1KDM4EMAPTHTTLMNA
SCHEMBL1728306 0.78 MAPK1 (0.47) MAPK1KDM4EMAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267060-B1 High-molecular polyazoles PBI PERFORMANCE PRODUCTS INC (US) 2014-09-17 EP claimed
EP-0758000-B1 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays DU PONT (US) 2001-12-19 EP claimed
EP-0616623-B1 POLYMERIC ALLOYS FROM POLYESTER RESINS AND PROCESS FOR THEIR PREPARATION SINCO RICERCHE SPA (IT) 2001-03-21 EP claimed
US-7471360-B2 Liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2008-12-30 US disclosed
US-20070046870-A1 Liquid crystal display device KONICA MINOLTA OPTO, INC. 2007-03-01 US disclosed