SCHEMBL8720840

SCHEMBL8720840

O=C(O)Oc1cc2ccc3c(OC(=O)O)c(OC(=O)O)ccc3c2cc1OC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 6/20 0.33
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
GRIN2D O15399 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2C Q14957 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
GAA P10253 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ADORA3 P0DMS8 2/20 0.30
PIM1 P11309 1/20 0.30
CSNK2A1 P68400 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723622 0.86 MAPK1 (0.32) KDM4EALDH1A1GAATSHRRAB9A
SCHEMBL8746463 0.84 PIM1 (0.34) NCEH1KDM4EALDH1A1GAATSHR
SCHEMBL4873463 0.84 MAPK1 (0.33) KDM4EALDH1A1GAATSHRRAB9A
SCHEMBL7826659 0.77 ALDH1A1 (0.42) NCEH1KDM4EALDH1A1GAAHPGD
SCHEMBL9360148 0.75 KDM4E (0.35) KDM4EALDH1A1GAATSHRRAB9A
SCHEMBL7068984 0.74 NCEH1 (0.45) NCEH1KDM4EALDH1A1GAARAB9A
SCHEMBL9649492 0.74 ESR1 (0.44) KDM4EALDH1A1GAATSHRRAB9A
SCHEMBL1039198 0.73 MAPK1 (0.36) CA12CA9KDM4EALDH1A1GAA
SCHEMBL9354051 0.72 KDM4E (0.32) KDM4EADORA3ADORA2AADORA1
SCHEMBL4872430 0.71 KDM4E (0.35) NCEH1CA12CA9KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648796-B1 Solutions of polyimide-forming substances and their use SCHENECTADY INT INC (US) 1998-08-26 EP disclosed
EP-0648796-A1 Solutions of polyimide-forming substances and their use BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0648795-A1 Solutions of polyimide-forming substances and their use as coating material BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0571899-B1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-B1 Method for forming patterned layers of heat-resistant polycondensates BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-A1 Method for forming patterned layers of heat-resistant polycondensates BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-15 EP disclosed
EP-0571899-A1 Radiation-curable mixture and its' use for producing high temperature-resistant relief structures BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-01 EP disclosed