SCHEMBL8723622

SCHEMBL8723622

O=C(O)Oc1ccc2c(ccc3c(OC(=O)O)c(OC(=O)O)ccc32)c1OC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.32
KDM4E B2RXH2 3/20 0.31
HTT P42858 2/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 2/20 0.31
GAA P10253 2/20 0.31
HPGD P15428 1/20 0.31
MPI P34949 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
ABCB11 O95342 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4873463 0.98 MAPK1 (0.33) MAPK1KDM4EHTTLMNAMAPT
SCHEMBL9649492 0.86 ESR1 (0.44) MAPK1KDM4EHTTMAPTSMN1; SMN2
SCHEMBL8720840 0.86 NCEH1 (0.33) KDM4EALDH1A1GAAHPGDTSHR
SCHEMBL1039198 0.85 MAPK1 (0.36) MAPK1KDM4EMAPTSMN1; SMN2TDP1
SCHEMBL8721229 0.82 HTT (0.37) KDM4EHTTLMNAMAPTSMN1; SMN2
SCHEMBL8746463 0.81 PIM1 (0.34) KDM4EMAPTTDP1ALDH1A1GAA
SCHEMBL9360148 0.80 KDM4E (0.35) MAPK1KDM4EHTTLMNAMAPT
SCHEMBL7068984 0.78 NCEH1 (0.45) MAPK1KDM4ELMNAMAPTSMN1; SMN2
SCHEMBL1551337 0.77 GABRP (0.33) MAPK1KDM4EHTTLMNAL3MBTL1
SCHEMBL1728306 0.76 MAPK1 (0.47) MAPK1KDM4EMAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648796-B1 Solutions of polyimide-forming substances and their use SCHENECTADY INT INC (US) 1998-08-26 EP disclosed
EP-0648796-A1 Solutions of polyimide-forming substances and their use BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0648795-A1 Solutions of polyimide-forming substances and their use as coating material BASF Lacke + Farben AG (DE) 1995-04-19 EP disclosed
EP-0573866-B1 Method for forming patterned layers of heat-resistant polycondensates BASF LACKE & FARBEN (DE) 1994-11-02 EP disclosed
EP-0573866-A1 Method for forming patterned layers of heat-resistant polycondensates BASF Lacke + Farben Aktiengesellschaft (DE) 1993-12-15 EP disclosed