Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.60 |
| ▸ | NOS2 | P35228 | 2/20 | 0.60 |
| ▸ | NOS1 | P29475 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1050198 | 0.96 | NOS3 (0.63) | NOS3NOS2NOS1POLBAPOBEC3G | |
| SCHEMBL7489 | 0.96 | — | — | |
| SCHEMBL9472907 | 0.96 | NOS3 (0.63) | NOS3NOS2NOS1POLBAPOBEC3G | |
| Hydrogen Sulfide SCHEMBL5051773 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G | |
| Iodide SCHEMBL20816339 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G | |
| Bromide SCHEMBL10623440 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G | |
| Fluoride SCHEMBL893225 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G | |
| SCHEMBL19816355 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G | |
| Hydrochloric Acid SCHEMBL458427 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G | |
| SCHEMBL28385227 | 0.93 | NOS3 (0.60) | NOS3NOS2NOS1POLBAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106200-B2 | Pyridine borane complexes | BASF SE (DE) | 2012-01-31 | — | — | US | disclosed |
| US-20110207934-A1 | PYRIDINE BORANE COMPLEXES | BASF SE (DE) | 2011-08-25 | — | — | US | disclosed |
| EP-2066631-B1 | PYRIDINE BORANE COMPLEXES | BASF SE (DE) | 2011-04-06 | — | — | EP | disclosed |
| EP-2007679-A2 | IMPROVED PROCESS FOR THE SYNTHESIS AND METHANOLYSIS OF AMMONIA BORANE AND BORAZINE | Purdue Research Foundation (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20070243122-A1 | Process for the synthesis and methanolysis of ammonia borane and borazine | PURDUE RESEARCH FOUNDATION | 2007-10-18 | — | — | US | disclosed |
| WO-2007106459-A2 | IMPROVED PROCESS FOR THE SYNTHESIS AND METHANOLYSIS OF AMMONIA BORANE AND BORAZINE | PURDUE RESEARCH FOUNDATION (US) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207934-A1 | PYRIDINE BORANE COMPLEXES | NBAS, BRD8, PAXBP1 | NOS3 3715/4885NOS2 3775/4885NOS1 3930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.