Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5351419 | 0.78 | PNMT (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL5853591 | 0.77 | PNMT (0.37) | NPC1RAB9APNMTDRD2DRD4 | |
| Fluoride Ion SCHEMBL1130432 | 0.75 | PNMT (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7641131 | 0.73 | PNMT (0.47) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL6557783 | 0.71 | PNMT (0.42) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7716977 | 0.70 | PNMT (0.47) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL29236923 | 0.69 | PNMT (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30661101 | 0.69 | PNMT (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL3119416 | 0.69 | PNMT (0.44) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL3124487 | 0.69 | NPC1 (0.49) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40234-E1 | Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system | EXXONMOBIL CHEMICAL PATENTS, INC. | 2008-04-08 | — | — | US | disclosed |
| US-7041841-B1 | Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-6613845-B1 | Propylene/ethylene-α-olefin block copolymer and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-02 | — | — | US | disclosed |
| EP-0548277-B1 | PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-5990242-A | Propylene/ethylene-α-olefin block copolymer and process for processing the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0548277-A1 | PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM | EXXON CHEMICAL PATENTS INC. (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005204-A1 | PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM | EXXON CHEMICAL PATENTS INC. (US) | 1992-04-02 | — | — | WO | disclosed |
| US-5026798-A | Coordination catalyst | EXXON CHEMICAL PATENTS INC. (US) | 1991-06-25 | — | — | US | disclosed |