SCHEMBL8585258

SCHEMBL8585258

C=CC(=O)OC1(CCCC)CC1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.47
HPGD P15428 1/20 0.47
THRB P10828 3/20 0.37
ALDH1A1 P00352 4/20 0.34
CYP3A4 P08684 1/20 0.34
THRA P10827 1/20 0.34
ZDHHC20 Q5W0Z9 2/20 0.33
ZDHHC2 Q9UIJ5 2/20 0.33
ATM Q13315 1/20 0.33
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2290619 0.95 TSHR (0.46) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL789233 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL790248 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL6917510 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL4401693 0.93 TSHR (0.44) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL29117687 0.92 TSHR (0.43) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL1648754 0.92 TSHR (0.43) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL48742 0.89 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28389452 0.88 TSHR (0.43) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL4401954 0.88 TSHR (0.40) TSHRHPGDTHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672083-B1 POLYMER BLENDS CONTAINING PROPYLENE-ETHYLENE COPOLYMER AND ETHYLENE-ALKYL ACRYLATE COPOLYMER CHEVRON CHEM CO (US) 1998-01-28 EP disclosed
EP-0672083-A1 POLYMER BLENDS CONTAINING PROPYLENE-ETHYLENE COPOLYMER AND ETHYLENE-ALKYL ACRYLATE COPOLYMER CHEVRON CHEMICAL COMPANY (US) 1995-09-20 EP disclosed
WO-1994012569-A1 POLYMER BLENDS CONTAINING PROPYLENE-ETHYLENE COPOLYMER AND ETHYLENE-ALKYL ACRYLATE COPOLYMER CHEVRON CHEMICAL COMPANY (US) 1994-06-09 WO disclosed
US-5272210-A Polymer blends containing propylene-ethylene copolymer and ethylene-alkyl acrylate copolymer CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1993-12-21 US disclosed