SCHEMBL2290619

SCHEMBL2290619

C=CC(=O)OC1(CCCCC)CC1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
HPGD P15428 1/20 0.46
THRB P10828 5/20 0.40
THRA P10827 3/20 0.36
ZDHHC20 Q5W0Z9 3/20 0.36
ZDHHC2 Q9UIJ5 2/20 0.36
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
ATM Q13315 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL789233 0.98 TSHR (0.44) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL790248 0.98 TSHR (0.44) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL6917510 0.98 TSHR (0.44) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL8585258 0.95 TSHR (0.47) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL28389452 0.93 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL1763961 0.89 TSHR (0.37) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL4401693 0.88 TSHR (0.44) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL48742 0.87 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL29117687 0.87 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL1648754 0.87 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6136201-A None JP disclosed
CN-117866315-A Low shrinkage tensile film SK新技术株式会社 2024-04-12 CN disclosed
EP-2843000-B1 A MOLDING COMPRISING A POLYCARBONATE RESIN COMPOSITION WITH SUPERIOR FLUIDITY AND A METHOD OF PRODUCING THE SAME KANEKA CORP (JP) 2021-10-06 EP disclosed
US-9944790-B2 Polycarbonate resin composition with superior fluidity and molding thereof KANEKA CORPORATION (JP) 2018-04-17 US disclosed
US-20150099106-A1 POLYCARBONATE RESIN COMPOSITION WITH SUPERIOR FLUIDITY AND MOLDING THEREOF KANEKA CORPORATION (JP) 2015-04-09 US disclosed
EP-2843000-A1 POLYCARBONATE RESIN COMPOSITION WITH SUPERIOR FLUIDITY AND MOLDING THEREOF Kaneka Corporation (JP) 2015-03-04 EP disclosed
US-8530087-B2 Secondary lithium battery HITACHI, LTD. (JP) 2013-09-10 US disclosed
US-7998895-B2 Catalysts for olefin polymerization E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-16 US disclosed
US-20110189541-A1 SECONDARY LITHIUM BATTERY HITACHI, LTD. (JP) 2011-08-04 US disclosed
US-20100222531-A1 CATALYSTS FOR OLEFIN POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-02 US disclosed
US-20050014003-A1 Thermoplastic resin composition and production method thereof MITSUBISHI RAYON CO., LTD. (JP) 2005-01-20 US disclosed
US-6541585-B2 Using transition metal complexes that have sites capable of binding a Lewis acid in close proximity to the metal center E. I. DU PONT DE NEMOURS AND COMPANY 2003-04-01 US disclosed
EP-1292624-A2 CATALYSTS FOR OLEFIN POLYMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-19 EP disclosed
EP-1292623-A2 POLYMERIZATION OF OLEFINS E. I. du Pont de Nemours and Company (US) 2003-03-19 EP disclosed
US-20020037982-A1 Polymerization of olefins E. I. DU PONT DE NEMOURS AND COMPANY 2002-03-28 US disclosed
WO-2001092342-A2 CATALYSTS FOR OLEFIN POLYMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-12-06 WO disclosed
WO-2001092347-A2 POLYMERIZATION OF OLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2001-12-06 WO disclosed
US-5434213-A Pressure sensitive adhesive with enhanced adhesion to low surface energy substrates ASHLAND OIL, INC. (US) 1995-07-18 US disclosed
JP-H06136201-A OLEFINIC COPOLYMER RESIN COMPOSITION OKAMOTO IND INC 1994-05-17 JP disclosed
US-4133796-A ETHYLENE COPOLYMER, RUBBER, PHENOLIC RESIN, EPOXY RESIN UNION CARBIDE CORPORATION (US) 1979-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100222531-A1 CATALYSTS FOR OLEFIN POLYMERIZATION PORCN, PUF60, CAD TSHR 4750/4885HPGD 998/4885THRB 4714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.