SCHEMBL487444

SCHEMBL487444

CCCCCCC#CCCO

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.56
HMGCR P04035 3/20 0.56
ALDH1A1 P00352 3/20 0.52
LMNA P02545 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
TSHR P16473 2/20 0.52
HSD17B10 Q99714 1/20 0.52
RECQL P46063 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
ALOX12 P18054 1/20 0.47
BLM P54132 1/20 0.47
MCL1 Q07820 1/20 0.47
SELP P16109 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2483643 1.00 PTPN7 (0.56) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL8684335 1.00 PTPN7 (0.56) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL2806902 1.00 PTPN7 (0.56) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL29479496 1.00 PTPN7 (0.56) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL487538 0.97 PTPN7 (0.52) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL10959870 0.93 PTPN7 (0.50) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL10960337 0.93 PTPN7 (0.50) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL10956905 0.93 PTPN7 (0.50) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL10962163 0.93 PTPN7 (0.50) PTPN7HMGCRALDH1A1LMNAMEN1
SCHEMBL15283605 0.90 HMGCR (0.59) PTPN7HMGCRALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7727692-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2010-06-01 US claimed
US-20080166615-A1 COOLING LIQUID COMPOSITION FOR FUEL CELL SHISHIAI-KABUSHIKIGAISHA (JP) 2008-07-10 US claimed
US-20070027297-A1 Modified polyethylenephosphinic acids and their salts CLARIANT FINANCE (BVI) LIMITED 2007-02-01 US claimed
US-20060145120-A1 Cooling liquid composition for fuel cell SHISHIAI-KABUSHIKIGAISHA (JP) 2006-07-06 US claimed
EP-1653544-A1 COOLING LIQUID COMPOSITION FOR FUEL CELL Shishiai-Kabushikigaisha (JP) 2006-05-03 EP claimed
US-20040176580-A1 Modified polyethylenephosphinic acids and their salts CLARIANT GMBH 2004-09-09 US claimed
US-6600067-B2 Reacting phosphorous acid (H3PO3) directly with alkynes CLARIANT GMBH (DE) 2003-07-29 US claimed
US-6583315-B2 Reacting yellow elemental phosphorus with an alkyl halide under alkaline conditions; acidifying, esterifying, isolating and hydrolyzing to obtain purified alkylphosphonous acid; reacting with acetylene CLARIANT GMBH (DE) 2003-06-24 US claimed
US-20030073865-A1 PROCESS FOR PREPARING ETHANEBIS(ALKYLPHOSPHINIC) ACIDS CLARIANT GMBH 2003-04-17 US claimed
US-20020082447-A1 Process for preparing ethylenediphosphonic acids CLARIANT GMBH 2002-06-27 US claimed
EP-0882080-B1 WATER-DISPERSIBLE POLYMER AND COATING COMPOSITION CONTAINING THE SAME DEXTER CORP (US) 2001-07-11 EP claimed
US-5922817-A COATING WHICH PROVIDES CORROSION RESISTANCE TO A METAL SUBSTRATE AND EXHIBITS EXCELLENT FLEXIBILITY, CHEMICAL RESISTANCE AND ADHESION THE DEXTER CORPORATION (US) 1999-07-13 US claimed
US-5869552-A HAVING STRUCTURE WITH EPOXY PORTION LINKED TO ACRYLIC PORTION BY COMPOUND HAVING EITHER CONJUGATED DOUBLE BONDS OR TRIPLE BOND AND MOIETY CAPABLE OF REACTING WITH EPOXY GROUP THE DEXTER CORPORATION (US) 1999-02-09 US claimed
EP-0882080-A1 WATER-DISPERSIBLE POLYMER AND COATING COMPOSITION CONTAINING THE SAME THE DEXTER CORPORATION (US) 1998-12-09 EP claimed
US-5830952-A ACRYLIC POLYMERS LINKED TO EPOXY COMPOUNDS OR POLYMERS THE DEXTER CORPORATION (US) 1998-11-03 US claimed
WO-1997031044-A1 WATER-DISPERSIBLE POLYMER AND COATING COMPOSITION CONTAINING THE SAME THE DEXTER CORPORATION (US) 1997-08-28 WO claimed
JP-55059129-A None JP disclosed
JP-1163147-A None JP disclosed
US-3995054-A MITICIDES ZOECON CORPORATION (US) 1976-11-30 US disclosed
US-3969384-A Esters of cyclopropane alkanoic acids ZOECON CORPORATION (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176580-A1 Modified polyethylenephosphinic acids and their salts PHOSPHO1, PTEN, PBRM1 PTPN7 549/4885HMGCR 2567/4885ALDH1A1 3923/4885
US-20030073865-A1 PROCESS FOR PREPARING ETHANEBIS(ALKYLPHOSPHINIC) ACIDS HAO2, ARSA, APEH PTPN7 1841/4885HMGCR 1844/4885ALDH1A1 912/4885
US-20020082447-A1 Process for preparing ethylenediphosphonic acids ENPP1, ALK, INPPL1 PTPN7 788/4885HMGCR 2950/4885ALDH1A1 2080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.