Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.56 |
| ▸ | HMGCR | P04035 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487444 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL8684335 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL2806902 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL29479496 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL487538 | 0.97 | PTPN7 (0.52) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10959870 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10960337 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10956905 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10962163 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL15283605 | 0.90 | HMGCR (0.59) | PTPN7HMGCRALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125614-A1 | IONIZABLE CATIONIC LIPIDS | AKAGERA MEDICINES, INC. (US) | 2026-05-07 | — | — | US | disclosed |
| US-12606773-B2 | Ionizable cationic lipids | AKAGERA MEDICINES, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-20260077038-A1 | LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF | AKAGERA MEDICINES, INC. (US) | 2026-03-19 | — | — | US | disclosed |
| US-20260069684-A1 | LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF | AKAGERA MEDICINES, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260055335-A1 | IONIZABLE CATIONIC LIPID COMPOUNDS | AKAGERA MEDICINES, INC. (US) | 2026-02-26 | — | — | US | disclosed |
| US-12331264-B2 | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof | AKAGERA MEDICINES, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| CN-119562806-A | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof | 阿卡格拉医药公司 | 2025-03-04 | — | — | CN | disclosed |
| US-20240325525-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | AKAGERA MEDICINES, INC. (US) | 2024-10-03 | — | — | US | disclosed |
| US-20240309291-A1 | IONIZABLE CATIONIC LIPIDS | AKAGERA MEDICINES, INC. (US) | 2024-09-19 | — | — | US | disclosed |
| US-12077725-B2 | Ionizable cationic lipids | AKAGERA MEDICINES, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-20120122972-A1 | NOVEL EICOSANOID DERIVATIVES | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (MDC) (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120122972-A1 | NOVEL EICOSANOID DERIVATIVES | MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (MDC) (DE) | 2012-05-17 | — | — | US | disclosed |
| EP-2376432-A1 | NOVEL EICOSANOID DERIVATIVES | Max-Delbrück-Centrum für Molekulare Medizin (MDC) (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010081683-A1 | NOVEL EICOSANOID DERIVATIVES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2010-07-22 | — | — | WO | disclosed |
| EP-2208720-A1 | Novel eicosanoid derivatives | Max-Delbrück-Centrum für Molekulare Medizin (MDC) (DE) | 2010-07-21 | — | — | EP | disclosed |
| EP-2208720-A1 | Novel eicosanoid derivatives | Max-Delbrück-Centrum für Molekulare Medizin (MDC) (DE) | 2010-07-21 | — | — | EP | disclosed |
| EP-0899286-A1 | Vinyl-group-containing dendrimer and curable composition | TOYO INK MANUFACTURING CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-4732756-A | INSECTICIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1988-03-22 | — | — | US | disclosed |
| US-4515727-A | ANTIALLERGY, ANTINFLAMMATORY | SYNTEX (U.S.A.) INC. (US) | 1985-05-07 | — | — | US | disclosed |
| US-4434101-A | SLOW REACTING SUBSTANCE OF ANAPHYLAXIS, ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1984-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260069684-A1 | LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF | PHOSPHO1, PLTP, SGMS1 | PTPN7 3118/4885HMGCR 1721/4885ALDH1A1 4716/4885 |
| US-20120122972-A1 | NOVEL EICOSANOID DERIVATIVES | FABP3, PTGER3, PTGES3 | PTPN7 4686/4885HMGCR 1017/4885ALDH1A1 646/4885 |
| US-12077725-B2 | Ionizable cationic lipids | PHOSPHO1, LIPA, ABHD16A | PTPN7 4600/4885HMGCR 2898/4885ALDH1A1 4099/4885 |
| US-20260077038-A1 | LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS AND METHODS OF USE THEREOF | PHOSPHO1, LNPK, SGMS2 | PTPN7 2678/4885HMGCR 2667/4885ALDH1A1 4782/4885 |
| US-20260125614-A1 | IONIZABLE CATIONIC LIPIDS | CPT2, NPC1L1, PNPLA2 | PTPN7 4752/4885HMGCR 865/4885ALDH1A1 3307/4885 |
| US-12606773-B2 | Ionizable cationic lipids | NPC1L1, MCOLN1, SLC22A4 | PTPN7 3533/4885HMGCR 2057/4885ALDH1A1 2574/4885 |
| US-20260055335-A1 | IONIZABLE CATIONIC LIPID COMPOUNDS | CD4, LDLR, CD2BP2 | PTPN7 4485/4885HMGCR 2789/4885ALDH1A1 2719/4885 |
| US-20240309291-A1 | IONIZABLE CATIONIC LIPIDS | PHOSPHO1, LIPA, ABHD16A | PTPN7 4600/4885HMGCR 2898/4885ALDH1A1 4099/4885 |
| US-20240325525-A1 | Lipid Nanoparticles for Delivery of Nucleic Acids and Methods of Use Thereof | PHOSPHO1, PTDSS1, PTDSS2 | PTPN7 3257/4885HMGCR 4495/4885ALDH1A1 4475/4885 |
| US-12331264-B2 | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof | ASGR1, LDLR, CD2BP2 | PTPN7 2879/4885HMGCR 2323/4885ALDH1A1 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.