Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.56 |
| ▸ | HMGCR | P04035 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483643 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL487444 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL8684335 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL29479496 | 1.00 | PTPN7 (0.56) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL487538 | 0.97 | PTPN7 (0.52) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10959870 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10960337 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10956905 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL10962163 | 0.93 | PTPN7 (0.50) | PTPN7HMGCRALDH1A1LMNAMEN1 | |
| SCHEMBL15283605 | 0.90 | HMGCR (0.59) | PTPN7HMGCRALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049099-A1 | DOUBLE-STRANDED SIRNA, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | YIMEICHENGJIAN SHANGHAI BIOMEDICAL CO LTD (CN) | 2026-02-19 | — | — | US | disclosed |
| CN-119241620-B | Double-stranded siRNA, preparation method, pharmaceutical composition and application thereof | 羿美诚健(上海)生物医药有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119241620-A | Double-stranded siRNA, preparation method, pharmaceutical composition and application thereof | 羿美诚健(上海)生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-2396418-A1 | METHODS FOR THE DETECTION OF FATTY-ACYLATED PROTEINS | Genentech, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010093916-A1 | METHODS FOR THE DETECTION OF FATTY-ACYLATED PROTEINS | GENENTECH, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| US-20100189660-A1 | METHODS FOR THE DETECTION OF FATTY-ACYLATED PROTEIN | GENENTECH, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049099-A1 | DOUBLE-STRANDED SIRNA, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | RNMT, NSUN2, RNGTT | PTPN7 4052/4885HMGCR 1228/4885ALDH1A1 346/4885 |
| US-20100189660-A1 | METHODS FOR THE DETECTION OF FATTY-ACYLATED PROTEIN | FABP1, DBI, FABP4 | PTPN7 1870/4885HMGCR 1571/4885ALDH1A1 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.