Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174251 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3174266 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3186852 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3186839 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3188185 | 0.83 | MAPT (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL3188169 | 0.83 | MAPT (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL19667048 | 0.79 | ITGA4 (0.65) | ALDH1A1SMN1; SMN2KDM4ENPSR1HTT | |
| SCHEMBL17177050 | 0.75 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2KDM4EHTTPKM | |
| SCHEMBL4876065 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL15714755 | 0.73 | MAPT (0.59) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |