Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL48746

N.N.Nc1cc(C(c2ccc(O)c(N)c2)(C(F)(F)F)C(F)(F)F)ccc1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.57
GAA P10253 7/20 0.57
MAPT P10636 4/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
PKM P14618 3/20 0.57
RECQL P46063 2/20 0.57
ESR1 P03372 3/20 0.48
ESR2 Q92731 2/20 0.48
CHEK1 O14757 1/20 0.42
FYN P06241 1/20 0.42
PDGFRB P09619 1/20 0.42
PIM1 P11309 1/20 0.42
FGFR1 P11362 1/20 0.42
FLT1 P17948 1/20 0.42
GRK5 P34947 1/20 0.42
MAP2K2 P36507 1/20 0.42
MAPK8 P45983 1/20 0.42
CDK8 P49336 1/20 0.42
RPS6KA3 P51812 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26579 0.98 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29360962 0.98 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29379543 0.98 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL8977755 0.96 ALDH1A1 (0.57) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL4295432 0.91 ALDH1A1 (0.52) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL14665668 0.89 ALDH1A1 (0.55) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL28561388 0.89 ALDH1A1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL13878423 0.89 ALDH1A1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
Questiomycin B SCHEMBL4623183 0.89 ALOX15 (0.52) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL14476250 0.89 ALDH1A1 (0.53) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8083834-B2 High permeability membrane operated at elevated temperature for upgrading natural gas UOP LLC (US) 2011-12-27 US claimed
US-20090277327-A1 High Permeability Membrane Operated at Elevated Temperature for Upgrading Natural Gas UOP LLC 2009-11-12 US claimed
US-10428253-B2 Photosensitive resin composition, film adhesive, adhesive sheet, adhesive pattern, semiconductor wafer with adhesive layer, and semiconductor device HITACHI CHEMICAL COMPANY, LTD (JP) 2019-10-01 US disclosed
US-20160160102-A1 PHOTOSENSITIVE RESIN COMPOSITION, FILM ADHESIVE, ADHESIVE SHEET, ADHESIVE PATTERN, SEMICONDUCTOR WAFER WITH ADHESIVE LAYER, AND SEMICONDUCTOR DEVICE RESONAC CORPORATION (JP) 2016-06-09 US disclosed
US-9138692-B2 Polymer membranes prepared from aromatic polyimide membranes by thermal treating and UV crosslinking UOP LLC (US) 2015-09-22 US disclosed
US-8613362-B2 Polymer membranes derived from aromatic polyimide membranes UOP LLC (US) 2013-12-24 US disclosed
US-20120276300-A1 POLYMER MEMBRANES PREPARED FROM AROMATIC POLYIMIDE MEMBRANES BY THERMAL TREATING AND UV CROSSLINKING UOP LLC (US) 2012-11-01 US disclosed
US-8241501-B2 Polymer membranes prepared from aromatic polyimide membranes by thermal treating and UV crosslinking UOP LLC (US) 2012-08-14 US disclosed
US-20120133061-A1 PHOTOSENSITIVE ADHESIVE, AND FILM ADHESIVE, ADHESIVE SHEET, ADHESIVE PATTERN, SEMICONDUCTOR WAFER WITH ADHESIVE LAYER, AND SEMICONDUCTOR DEVICE, WHICH ARE MADE USING SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-05-31 US disclosed
US-8132677-B2 Polymer membranes prepared from aromatic polyimide membranes by thermal treating and UV crosslinking UOP LLC (US) 2012-03-13 US disclosed
US-8127936-B2 High performance cross-linked polybenzoxazole and polybenzothiazole polymer membranes UOP LLC (US) 2012-03-06 US disclosed
WO-2010110994-A2 POLYMER MEMBRANES PREPARED FROM AROMATIC POLYIMIDE MEMBRANES BY THERMAL TREATING AND UV CROSSLINKING UOP LLC (US) 2010-09-30 WO disclosed
WO-2010110975-A2 HIGH PERFORMANCE CROSS-LINKED POLYBENZOXAZOLE AND POLYBENZOTHIAZOLE POLYMER MEMBRANES UOP LLC (US) 2010-09-30 WO disclosed
US-20100137124-A1 High Performance Cross-Linked Polybenzoxazole and Polybenzothiazole Polymer Membranes UOP LLC 2010-06-03 US disclosed
US-20100133192-A1 Polymer Membranes Prepared from Aromatic Polyimide Membranes by Thermal Treating and UV Crosslinking UOP LLC 2010-06-03 US disclosed
US-20100133186-A1 High Performance Cross-Linked Polybenzoxazole and Polybenzothiazole Polymer Membranes UOP LLC 2010-06-03 US disclosed
US-20040082732-A1 Crosslinkable oligoimides FRANCE TELECOM (FR) 2004-04-29 US disclosed
WO-2002057845-A9 CROSSLINKABLE OLIGOIMIDES FRANCE TELECOM (FR) 2004-04-01 WO disclosed
EP-1354242-A1 CROSSLINKABLE OLIGOIMIDES FRANCE TELECOM (FR) 2003-10-22 EP disclosed
WO-2002057845-A1 CROSSLINKABLE OLIGOIMIDES FRANCE TELECOM (FR) 2002-07-25 WO disclosed