Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935580 | 0.85 | BDKRB1 (0.36) | BDKRB1MAP4K1SLC6A3BACE1SLC6A2 | |
| SCHEMBL3930247 | 0.84 | KCNH2 (0.38) | NR1H4TLR9TLR8 | |
| SCHEMBL4877262 | 0.82 | MAPK1 (0.33) | BDKRB1MAP4K1SLC6A3BACE1SLC6A2 | |
| SCHEMBL2987900 | 0.78 | HTR2A (0.39) | NR1H4SLC6A3CDK1 | |
| SCHEMBL3941890 | 0.78 | ALDH1A1 (0.36) | BDKRB1MAP4K1SLC6A3BACE1SLC6A2 | |
| SCHEMBL2995078 | 0.77 | HTR2A (0.39) | SLC6A3 | |
| SCHEMBL2156442 | 0.76 | KDM4E (0.41) | NR1H4MAPTTLR9CDK1 | |
| SCHEMBL2868300 | 0.75 | KDM4E (0.41) | NR1H4MAPTTLR9TLR8CDK1 | |
| SCHEMBL3000692 | 0.75 | SLC6A3 (0.40) | NR1H4SLC6A3SLC6A2SLC6A4MAPT | |
| SCHEMBL2157791 | 0.74 | KDM4E (0.39) | NR1H4MAPTTLR9CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | BDKRB1 3920/4885NR1H4 2044/4885MAP4K1 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.