Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874831 | 0.91 | ALDH1A1 (0.36) | ALDH1A1SCN9APIK3CAMTORSLC8A1 | |
| SCHEMBL4877344 | 0.88 | SCN9A (0.37) | SCN9APIK3CAMTORSLC8A1 | |
| SCHEMBL4877312 | 0.87 | PIK3CA (0.43) | ALDH1A1PIK3CAMTORMAPTALOX15 | |
| SCHEMBL4877380 | 0.87 | SCN9A (0.34) | SCN9ASLC8A1 | |
| SCHEMBL4866941 | 0.86 | SCN9A (0.35) | SCN9ASLC8A1 | |
| SCHEMBL4874047 | 0.86 | TP53 (0.44) | ALDH1A1PIK3CAMTORMAPTWNK1 | |
| SCHEMBL4878179 | 0.85 | PIK3CA (0.42) | ALDH1A1PIK3CAMTORMAPTALOX15 | |
| SCHEMBL4873044 | 0.84 | PIK3CA (0.38) | ALDH1A1PIK3CAMTORMAPTALOX15 | |
| SCHEMBL4877171 | 0.84 | PIK3CA (0.43) | PIK3CAMTORSMOWNK1UBE2M | |
| SCHEMBL4866875 | 0.82 | ALDH1A1 (0.39) | ALDH1A1PIK3CAMTORMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051384-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | ALDH1A1 1357/4885SCN9A 2977/4885PIK3CA 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.