SCHEMBL487487

SCHEMBL487487

CN(C)C(=O)c1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.61
ALDH1A1 P00352 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
PDK2 Q15119 3/20 0.56
HSP90AA1 P07900 1/20 0.56
ESR1 P03372 2/20 0.52
ESR2 Q92731 2/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
PDK4 Q16654 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26680622 0.93 HSD17B1 (0.59) HPGDALDH1A1SMN1; SMN2PDK2HSP90AA1
SCHEMBL1004649 0.89 ALDH1A1 (0.73) HPGDALDH1A1SMN1; SMN2PDK2HSP90AA1
SCHEMBL10626283 0.82 ALDH1A1 (0.64) HPGDALDH1A1SMN1; SMN2PDK2LMNA
SCHEMBL469413 0.80 ALDH1A1 (0.61) HPGDALDH1A1SMN1; SMN2LMNAPKM
SCHEMBL1300109 0.80 ALDH1A1 (0.61) HPGDALDH1A1SMN1; SMN2PDK2HSP90AA1
SCHEMBL949041 0.80 HPGD (0.61) HPGDALDH1A1SMN1; SMN2PDK2HSP90AA1
SCHEMBL458926 0.80 ALDH1A1 (0.61) HPGDALDH1A1SMN1; SMN2CA1CA2
SCHEMBL6802143 0.79 HSP90AA1 (0.60) HPGDALDH1A1PDK2HSP90AA1ESR1
SCHEMBL24783913 0.78 ALDH1A1 (0.67) HPGDALDH1A1SMN1; SMN2PDK2HSP90AA1
SCHEMBL1004065 0.78 ALDH1A1 (0.59) HPGDALDH1A1SMN1; SMN2PDK2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707859-A Para-substituted heptamethine quinone cyanine dye and synthetic method and application thereof 大连理工大学 2025-03-28 CN claimed
CN-116537266-A Anti-floating anchor rod waterproof structure and construction method 华通建设发展集团有限公司 2023-08-04 CN claimed
US-10240003-B2 Poly(aryl ether sulfone) composition and method of making SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-26 US claimed
EP-2773684-B1 POLY(ARYL ETHER SULFONE) COMPOSITION AND METHOD OF MAKING SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-30 EP claimed
US-9040651-B2 Poly(aryl ether sulfone) composition, and method of making SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-05-26 US claimed
US-20140350207-A1 POLY(ARYL ETHER SULFONE) COMPOSITION AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-11-27 US claimed
EP-2773684-A1 POLY(ARYL ETHER SULFONE) COMPOSITION AND METHOD OF MAKING SABIC Innovative Plastics IP B.V. (NL) 2014-09-10 EP claimed
WO-2013066784-A1 POLY(ARYL ETHER SULFONE) COMPOSITION AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-05-10 WO claimed
US-20130109831-A1 POLY(ARYL ETHER SULFONE) COMPOSITION, AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-05-02 US claimed
CN-101553493-A Novel tricyclic spiropiperidine compounds, their synthesis and their use as modulators of chemokine receptor activity ASTRAZENECA AB (SE) 2009-10-07 CN claimed
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 US disclosed
EP-4107164-B1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2025-12-03 EP disclosed
WO-2025202488-A1 ENHANCER OF NUCLEIC ACID AMPLIFICATION ROCHE DIAGNOSTICS GMBH (DE) 2025-10-02 WO disclosed
US-20250296938-A1 Compounds that Interact with the Ras Superfamily for the Treatment of Cancers, Inflammatory Diseases, Rasopathies, and Fibrotic Disease SHY Therapeutics LLC (US) 2025-09-25 US disclosed
US-12391705-B2 Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease SHY THERAPEUTICS, LLC (US) 2025-08-19 US disclosed
US-4146541-A YELLOW SHADE ON POLYESTERS CIBA-GEIGY AG (CH) 1979-03-27 US disclosed
US-4140836-A PRIMERS, WATERPROOFING, ADHESION PPG INDUSTRIES, INC. (US) 1979-02-20 US disclosed
US-4098740-A PRIMER COATINGS, POLYEPOXIDES, PHENOLS PPG INDUSTRIES, INC. (US) 1978-07-04 US disclosed
US-4031051-A Hydrolyzed reaction product of a polyepoxide with a phenolic compound having a group hydrolyzable to a carboxyl and curing agent therefor PPG INDUSTRIES, INC. (US) 1977-06-21 US disclosed
US-3960795-A Hydrolyzed reaction product of a polyepoxide with a phenolic compound having a group hydrolyzable to carboxyl PPG INDUSTRIES, INC. (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 HPGD 3520/4885ALDH1A1 744/4885SMN1; SMN2 111/4885
US-12391705-B2 Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease HRAS, KRAS, NRAS HPGD 2093/4885ALDH1A1 3359/4885SMN1; SMN2 3538/4885
US-20250296938-A1 Compounds that Interact with the Ras Superfamily for the Treatment of Cancers, Inflammatory Diseases, Rasopathies, and Fibrotic Disease HRAS, KRAS, NRAS HPGD 2093/4885ALDH1A1 3359/4885SMN1; SMN2 3538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.