Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884137 | 0.92 | CYP1A2 (0.48) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9990265 | 0.81 | MEN1 (0.44) | OPRK1DRD2OPRM1DRD3OPRD1 | |
| Water SCHEMBL29140161 | 0.79 | MEN1 (0.43) | OPRK1DRD2OPRM1DRD3OPRD1 | |
| SCHEMBL4880979 | 0.78 | TSHR (0.47) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10024147 | 0.77 | ALDH1A1 (0.54) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9136823 | 0.77 | TSHR (0.46) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9330111 | 0.76 | CYP1A2 (0.44) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10024145 | 0.75 | GAA (0.46) | CYP1A2TSHRCYP3A4CYP2C9CYP2C19 | |
| Water SCHEMBL28973048 | 0.74 | KCNH2 (0.46) | OPRK1DRD2OPRM1DRD3OPRD1 | |
| SCHEMBL27819823 | 0.74 | KCNH2 (0.50) | OPRK1DRD2OPRM1DRD3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541726-A | Process for preparing quinone methide | GEN ELECTRIC (US) | 2009-09-23 | — | — | CN | disclosed |
| WO-2008067012-A1 | PROCESS FOR THE PRODUCTION OF QUINONE METHIDE | GENERAL ELECTRIC COMPANY (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080132726-A1 | PROCESS FOR THE PRODUCTION OF QUINONE METHIDE | GENERAL ELECTRIC COMPANY | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132726-A1 | PROCESS FOR THE PRODUCTION OF QUINONE METHIDE | NQO2, SQOR, MT-ND6 | CYP1A2 135/4885TSHR 3910/4885CYP3A4 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.