Sugi Predict

Sugi Predict / Compounds / Styrene

Styrene

Styrene

SCHEMBL4875616

C=CCOS(=O)(=O)O.C=Cc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.48
▸ TSHR P16473 2/20 0.48
▸ TDP1 Q9NUW8 1/20 0.43
▸ CYP3A4 P08684 1/20 0.40
▸ MEN1 O00255 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ LIG1 P18858 1/20 0.36
▸ MCL1 Q07820 2/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ PTPRC P08575 1/20 0.34
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL44761 0.85 CYP3A4 (0.36) ALDH1A1TSHRCYP3A4GAALIG1
Phenol SCHEMBL325759 0.84 ESR1 (0.42) ALDH1A1TSHRTDP1CYP3A4GAA
Naphthalene SCHEMBL626600 0.84 CYP3A4 (0.43) ALDH1A1TSHRTDP1CYP3A4MEN1
Phenol SCHEMBL17304228 0.83 ESR1 (0.41) ALDH1A1TSHRTDP1CYP3A4GAA
Diphenylether SCHEMBL19733094 0.83 HTT (0.43) ALDH1A1TSHRTDP1CYP3A4MEN1
Styrene SCHEMBL5769891 0.81 ALDH1A1 (0.47) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL7888603 0.81 TSHR (0.39) ALDH1A1TSHRTDP1CYP3A4GAA
Allylbenzene SCHEMBL1496239 0.81 CNR2 (0.43) ALDH1A1TSHRTDP1CYP3A4MEN1
Styrene SCHEMBL28307246 0.80 CA12 (0.49) ALDH1A1TSHRTDP1MEN1KMT2A
Styrene SCHEMBL1261405 0.79 ALDH1A1 (0.70) ALDH1A1TSHRTDP1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7364599-B2 Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel SOUTHWEST RESEARCH INSTITUTE (US) 2008-04-29 — — US claimed
US-20040249233-A1 Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel SOUTHWEST RESEARCH INSTITUTE 2004-12-09 — — US claimed
US-7364599-B2 Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel SOUTHWEST RESEARCH INSTITUTE (US) 2008-04-29 — — US disclosed
WO-2005087902-A1 METHODS FOR INCREASED REMOVAL OF DRAG REDUCER ADDITIVES FROM LIQUID HYDROCARBON FUEL SOUTHWEST RESEARCH INSTITUTE (US) 2005-09-22 — — WO disclosed
US-20040249233-A1 Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel SOUTHWEST RESEARCH INSTITUTE 2004-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040249233-A1 Methods for increased removal of drag reducer additives from liquid hydrocarbon fuel GRHPR, BLVRB, DENR ALDH1A1 1366/4885TSHR 454/4885TDP1 1586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.