Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CLPP | Q16740 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885735 | 0.82 | — | — | |
| SCHEMBL4881580 | 0.77 | HSD17B10 (0.35) | HSP90AB1HSD17B10TRPV1LMNAMAPT | |
| SCHEMBL4882883 | 0.73 | USP2 (0.33) | HSP90AB1HSD17B10LMNAMAPTHTT | |
| SCHEMBL15319631 | 0.69 | MEN1 (0.56) | MAPTCLPP | |
| SCHEMBL4619486 | 0.67 | PDK2 (0.32) | MAPT | |
| SCHEMBL4619490 | 0.67 | TRPA1 (0.39) | HSD17B10TRPV1LMNAMAPTHTT | |
| SCHEMBL4624366 | 0.67 | TRPA1 (0.34) | HSD17B10MAPTNPSR1SMN1; SMN2CYP1A2 | |
| SCHEMBL28758727 | 0.67 | TLR8 (0.36) | HSD17B10LMNAMAPTHTTNPSR1 | |
| SCHEMBL4622389 | 0.66 | TRPA1 (0.38) | HSD17B10MAPTNPSR1SMN1; SMN2CYP1A2 | |
| SCHEMBL4882039 | 0.66 | USP2 (0.33) | HSP90AB1HSD17B10MAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | PFIZER INC | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234252-A1 | Compounds Useful in Therapy | AVPR1A, AVPR1B, AVPR2 | HSP90AB1 2905/4885HSD17B10 1110/4885TRPV1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.